(1 reference)-
- 抗原 See all NR1H3 抗体
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
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抗原表位
- AA 371-385, C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NR1H3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Oxysterols receptor LXR-alpha(NR1H3) detection. Tested with WB in Human,Mouse,Rat.
- 序列
- NVQDQLQVER LQHTY
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Oxysterols receptor LXR-alpha(NR1H3) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: nuclear receptor subfamily 1, group H, member 3
Protein Name: Oxysterols receptor LXR-alpha - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human LXR alpha(371-385aa NVQDQLQVERLQHTY), identical to the related rat and mouse sequences.
- 亚型
- IgG
- Top Product
- Discover our top product NR1H3 Primary Antibody
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anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) antibody
NR1H3 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (C-Term) antibodyNR1H3 适用: 人, 小鼠, 大鼠, Cow, 非洲爪蟾, 犬, 山羊, 马, 兔, Pig, 豚鼠, 猴, 斑马鱼, 小鸡, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 1-387) antibodyNR1H3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E9 unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 50-330) antibodyNR1H3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 1-402) antibodyNR1H3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 1-402) antibodyNR1H3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (C-Term) antibodyNR1H3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 50-150) antibodyNR1H3 适用: 人, 小鼠, 大鼠, 猴, 小鸡, 灵长类 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (N-Term) antibodyNR1H3 适用: 人, 小鼠 WB, ChIP-seq, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (AA 361-447) antibodyNR1H3 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Sodium azide, Thimerosal (Merthiolate)
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Fibroblast growth factor 21 enhances cholesterol efflux in THP-1 macrophage-derived foam cells." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 503-8, (2014) (PubMed).
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: "Fibroblast growth factor 21 enhances cholesterol efflux in THP-1 macrophage-derived foam cells." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 503-8, (2014) (PubMed).
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- 抗原
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
- 别名
- NR1H3 (NR1H3 产品)
- 别名
- NR1H3 antibody, LXR-a antibody, LXRA antibody, RLD-1 antibody, AU018371 antibody, LXR antibody, RLD1 antibody, Unr1 antibody, LXRalpha antibody, LXR-alpha antibody, im:7141239 antibody, wu:fd59b01 antibody, zgc:113339 antibody, zgc:158542 antibody, nuclear receptor subfamily 1 group H member 3 antibody, nuclear receptor subfamily 1, group H, member 3 antibody, NR1H3 antibody, nr1h3 antibody, Nr1h3 antibody
- 背景
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LXRA is a tissue-specific cofactor that permits RXRA to function as a potent 9cRA receptor with a distinct target gene specificity. It specifically interacts with RXRA in vivo to form a functional heterodimer in which RXRA is the ligand-binding subunit. Additionally, LXR activity is critical for physiologic lipid metabolism and transport. LXRs are endogenous inhibitors of atherogenesis and are targets for therapeutic intervention in cardiovascular disease. Furthermore, LXRs and their ligands are negative regulators of macrophage inflammatory gene expression. LXR is also found that as a transcriptional switch that integrates hepatic glucose metabolism and fatty acid synthesis. The LXR-IDOL-LDLR axis defines a complementary pathway to sterol response element-binding proteins for sterol regulation of cholesterol uptake.
Synonyms: Liver X receptor alpha antibody|LXR a antibody|LXRA antibody|NR1H3 antibody|NR1H3_HUMAN antibody|Nuclear orphan receptor LXR alpha antibody|Nuclear receptor subfamily 1 group H member 3 antibody|Oxysterols receptor LXR alpha antibody|Oxysterols receptor LXR-alpha antibody|RLD 1 antibody|RLD1 antibody - UniProt
- Q13133
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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