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RRAGA 抗体 (C-Term)

RRAGA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5517617
发货至: 中国
  • 抗原 See all RRAGA 抗体
    RRAGA (Ras-Related GTP Binding A (RRAGA))
    抗原表位
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 26
    • 12
    • 12
    • 1
    宿主
    • 26
    克隆类型
    • 25
    • 1
    多克隆
    标记
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RRAGA antibody is un-conjugated
    应用范围
    • 12
    • 11
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    CKEQRDVHRF EKISNIIKQF KLSCSKLAAS FQSMEVRNSN FAAFIDIFTS
    产品特性
    This is a rabbit polyclonal antibody against RRAGA. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human RRAGA
    Top Product
    Discover our top product RRAGA Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    RRAGA (Ras-Related GTP Binding A (RRAGA))
    别名
    RRAGA (RRAGA 产品)
    别名
    FIP-1 antibody, FIP1 antibody, RAGA antibody, 1300010C19Rik antibody, AI255374 antibody, Raga antibody, Ras related GTP binding A antibody, Ras-related GTP binding A antibody, RRAGA antibody, Rraga antibody
    背景
    RRAGA is a guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. It may play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. Also it may alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.

    Alias Symbols: RRAGA,

    Protein Interaction Partner: RRAGC, RPTOR, STAU1, UBC, IL7R, ASAP1, CPSF2, CPSF3, CPSF1, CSTF2T, PAPOLA, CPSF4, CSTF3, CDC73, LAMTOR1, NOL8, RRAGA, RRAGD,

    Protein Size: 313
    基因ID
    10670
    NCBI登录号
    NP_006561
    UniProt
    Q7L523
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