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RRAGA 抗体 (C-Term)

RRAGA 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264863
发货至: 中国
  • 抗原 See all RRAGA 抗体
    RRAGA (Ras-Related GTP Binding A (RRAGA))
    抗原表位
    • 6
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 25
    • 11
    • 11
    • 1
    人, 小鼠, 大鼠
    宿主
    • 25
    克隆类型
    • 24
    • 1
    多克隆
    标记
    • 11
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RRAGA antibody is un-conjugated
    应用范围
    • 11
    • 10
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    ELISA, Western Blotting (WB)
    特异性
    RRAGA Antibody detects endogenous levels of total RRAGA.
    预测反应
    Pig,Zebrafish,Bovine,Sheep,Rabbit,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human RRAGA, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product RRAGA Primary Antibody
  • 应用备注
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    RRAGA (Ras-Related GTP Binding A (RRAGA))
    别名
    RRAGA (RRAGA 产品)
    别名
    FIP-1 antibody, FIP1 antibody, RAGA antibody, 1300010C19Rik antibody, AI255374 antibody, Raga antibody, Ras related GTP binding A antibody, Ras-related GTP binding A antibody, RRAGA antibody, Rraga antibody
    背景

    Description: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.

    Gene: RRAGA

    分子量
    37 kDa
    基因ID
    10670
    UniProt
    Q7L523
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