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MASP1 抗体 (Middle Region)

MASP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5517538
发货至: 中国
  • 抗原 See all MASP1 抗体
    MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
    抗原表位
    • 15
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 49
    • 20
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 44
    • 5
    • 1
    克隆类型
    • 46
    • 4
    多克隆
    标记
    • 22
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MASP1 antibody is un-conjugated
    应用范围
    • 45
    • 23
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    VGPKVLGPFC GEKAPEPIST QSHSVLILFH SDNSGENRGW RLSYRAAGNE
    产品特性
    This is a rabbit polyclonal antibody against MASP1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of Human MASP1
    Top Product
    Discover our top product MASP1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
    别名
    MASP1 (MASP1 产品)
    别名
    AW048060 antibody, CCPII antibody, Crarf antibody, Masp1/3 antibody, 3MC1 antibody, CRARF antibody, CRARF1 antibody, MAP1 antibody, MASP antibody, MASP3 antibody, MAp44 antibody, PRSS5 antibody, RaRF antibody, mannan-binding lectin serine peptidase 1 antibody, mannan binding lectin serine peptidase 1 antibody, Masp1 antibody, MASP1 antibody
    背景
    This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.

    Alias Symbols: MASP1, CRARF, CRARF1, PRSS5,

    Protein Interaction Partner: CDK19, CUL3, PDCD6IP, RPS6KA6, MAPK8IP2, NUDT21, NCK2, UFD1L, RPS6KA3, MAPK6, H2AFX, GSK3B, GADD45A, C2, SERPING1, FCN2, MBL2, C3, MASP2,

    Protein Size: 380
    基因ID
    5648
    途径
    Complement System
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