HLA-A 抗体 (C-Term)
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北京 101111
Quick Overview for HLA-A 抗体 (C-Term) (ABIN5517133)
抗原
See all HLA-A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- HLA-A Antibody - C-terminal region
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序列
- QPTIPIVGII AGLVLLGAVI TGAVVAAVMW RRKSSDRKGG SYTQAASSDS
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human HLA-A
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anti-Major Histocompatibility Complex, Class I, A (HLA-A) (AA 1-365) antibody
HLA-A 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) (AA 24-365) antibodyHLA-A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D6 unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) (AA 1-365) antibodyHLA-A 适用: 人 FACS, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) antibodyHLA-A 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) (N-Term) antibodyHLA-A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) antibodyHLA-A 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal 108-2C5 unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) (AA 70-99) antibodyHLA-A 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) antibodyHLA-A 适用: 人 FACS, IF, IHC 宿主: 小鼠 Monoclonal CATA-1 unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) (AA 70-99) antibodyHLA-A 适用: 小鼠 WB 宿主: 小鼠 Monoclonal 7G7F9 unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) (C-Term) antibodyHLA-A 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP76263-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- HLA-A (Major Histocompatibility Complex, Class I, A (HLA-A))
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别名
- HLA-A
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背景
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Background Information: HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described.
Gene Name: Major histocompatibility complex, class I, A
Alternative Symbols: HLAA
Protein Name: HLA class I histocompatibility antigen, A-1 alpha chain
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分子量
- 41 kDa
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基因ID
- 3105
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NCBI登录号
- NP_001229687
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UniProt
- P30443
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途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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