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FLT3 抗体 (N-Term)

FLT3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5516496
发货至: 中国
  • 抗原 See all FLT3 抗体
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    抗原表位
    • 19
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    N-Term
    适用
    • 155
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    宿主
    • 157
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    克隆类型
    • 158
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    多克隆
    标记
    • 67
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    This FLT3 antibody is un-conjugated
    应用范围
    • 126
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    Western Blotting (WB)
    序列
    FGTITNQDLP VIKCVLINHK NNDSSVGKSS SYPMVSESPE DLGCALRPQS
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human FLT3
    Top Product
    Discover our top product FLT3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    别名
    FLT3 (FLT3 产品)
    别名
    FLT3 antibody, B230315G04 antibody, CD135 antibody, Flk-2 antibody, Flk2 antibody, Flt-3 antibody, Ly72 antibody, wmfl antibody, FLK-2 antibody, FLK2 antibody, STK1 antibody, fms related tyrosine kinase 3 antibody, FMS-like tyrosine kinase 3 antibody, fms-related tyrosine kinase 3 antibody, FLT3 antibody, Flt3 antibody
    背景
    This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

    Alias Symbols: FLK2, STK1, CD135, FLK-2

    Protein Size: 952
    基因ID
    2322
    NCBI登录号
    NM_004119, NP_004110
    途径
    RTK signaling
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