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CYP27B1 抗体 (C-Term)

CYP27B1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5516283
发货至: 中国
  • 抗原 See all CYP27B1 抗体
    CYP27B1 (Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1))
    抗原表位
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 16
    • 9
    • 7
    • 5
    宿主
    • 29
    • 2
    克隆类型
    • 29
    • 2
    多克隆
    标记
    • 16
    • 5
    • 5
    • 4
    • 1
    This CYP27B1 antibody is un-conjugated
    应用范围
    • 19
    • 19
    • 7
    • 7
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    FRPARWLGEG PTPHPFASLP FGFGKRSCMG RRLAELELQM ALAQILTHFE
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human CYP27B1
    Top Product
    Discover our top product CYP27B1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CYP27B1 (Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1))
    别名
    CYP27B1 (CYP27B1 产品)
    别名
    cp2b antibody, cyp1 antibody, cyp1alpha antibody, cyp27b antibody, p450c1 antibody, pddr antibody, vdd1 antibody, vddr antibody, vddri antibody, vdr antibody, CP2B antibody, CYP1 antibody, CYP1alpha antibody, CYP27B antibody, P450c1 antibody, PDDR antibody, VDD1 antibody, VDDR antibody, VDDRI antibody, VDR antibody, Cyp40 antibody, Cp2b antibody, Cyp1 antibody, Cyp27b antibody, Pddr antibody, Vdd1 antibody, Vddr antibody, VddrI antibody, Vdr antibody, cytochrome P450 family 27 subfamily B member 1 antibody, cytochrome P450, family 27, subfamily B, polypeptide 1 antibody, cytochrome P450, family 27, subfamily b, polypeptide 1 antibody, cyp27b1 antibody, CYP27B1 antibody, Cyp27b1 antibody
    背景
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I.

    Alias Symbols: VDR, CP2B, CYP1, PDDR, VDD1, VDDR, VDDRI, CYP27B, P450c1, CYP1alpha

    Protein Size: 508
    基因ID
    1594
    NCBI登录号
    NM_000785, NP_000776
    UniProt
    O15528
    途径
    Metabolism of Steroid Hormones and Vitamin D
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