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CYP27B1 抗体 (C-Term)
CYP27B1
适用: 人
WB
宿主: 兔
Polyclonal
unconjugated
CYP27B1抗体详情
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抗原
See all CYP27B1 抗体
CYP27B1
(Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1))
抗原表位
All epitopes for CYP27B1 抗体
C-Term
适用
All reactivities for CYP27B1 抗体
人
宿主
All hosts for CYP27B1 抗体
兔
克隆类型
All clonalities for CYP27B1 抗体
多克隆
标记
All conjugates for CYP27B1 抗体
This CYP27B1 antibody is un-conjugated
应用范围
All applications for CYP27B1 抗体
Western Blotting (WB)
序列
FRPARWLGEG PTPHPFASLP FGFGKRSCMG RRLAELELQM ALAQILTHFE
纯化方法
Affinity purified
免疫原
The immunogen is a synthetic peptide directed towards the C terminal region of human CYP27B1
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Discover our top product CYP27B1 Primary Antibody
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
CYP27B1目标详情
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抗原
CYP27B1
(Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1))
别名
CYP27B1 (CYP27B1 产品 )
别名
cp2b antibody, cyp1 antibody, cyp1alpha antibody, cyp27b antibody, p450c1 antibody, pddr antibody, vdd1 antibody, vddr antibody, vddri antibody, vdr antibody, CP2B antibody, CYP1 antibody, CYP1alpha antibody, CYP27B antibody, P450c1 antibody, PDDR antibody, VDD1 antibody, VDDR antibody, VDDRI antibody, VDR antibody, Cyp40 antibody, Cp2b antibody, Cyp1 antibody, Cyp27b antibody, Pddr antibody, Vdd1 antibody, Vddr antibody, VddrI antibody, Vdr antibody, cytochrome P450 family 27 subfamily B member 1 antibody, cytochrome P450, family 27, subfamily B, polypeptide 1 antibody, cytochrome P450, family 27, subfamily b, polypeptide 1 antibody, cyp27b1 antibody, CYP27B1 antibody, Cyp27b1 antibody
背景
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I. Alias Symbols: VDR, CP2B, CYP1, PDDR, VDD1, VDDR, VDDRI, CYP27B, P450c1, CYP1alpha Protein Size: 508
基因ID
1594
NCBI登录号
NM_000785 , NP_000776
UniProt
O15528
途径
Metabolism of Steroid Hormones and Vitamin D
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