PIP5K1A 抗体 (Middle Region)
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- 抗原 See all PIP5K1A 抗体
- PIP5K1A (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, alpha (PIP5K1A))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIP5K1A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- GGKNIRIVVM NNLLPRSVKM HIKYDLKGST YKRRASQKER EKPLPTFKDL
- 产品特性
- This is a rabbit polyclonal antibody against PIP5K1A. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human PIP5K1A
- Top Product
- Discover our top product PIP5K1A Primary Antibody
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anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, alpha (PIP5K1A) (AA 1-500) antibody
PIP5K1A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, alpha (PIP5K1A) (AA 293-562) antibodyPIP5K1A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, alpha (PIP5K1A) (N-Term) antibodyPIP5K1A 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, alpha (PIP5K1A) (AA 19-50), (N-Term) antibodyPIP5K1A 适用: 人 WB 宿主: 兔 Polyclonal RB01727 unconjugated
anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, alpha (PIP5K1A) antibodyPIP5K1A 适用: 人, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, alpha (PIP5K1A) (AA 258-347) antibodyPIP5K1A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PIP5K1A (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, alpha (PIP5K1A))
- 别名
- PIP5K1A (PIP5K1A 产品)
- 别名
- Pip5k1b antibody, pip5k1c antibody, PIP5K1A antibody, pip5k1b antibody, Pipk5a antibody, Pipk5b antibody, pip5k1a antibody, zgc:110576 antibody, im:7140933 antibody, zgc:158838 antibody, phosphatidylinositol-4-phosphate 5-kinase type 1 alpha antibody, phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, alpha L homeolog antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, alpha antibody, phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b antibody, PIP5K1A antibody, Pip5k1a antibody, pip5k1a.L antibody, pip5k1a antibody, pip5k1aa antibody, pip5k1ab antibody
- 背景
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PIP5K1A catalyzes the phosphorylation of phosphatidylinositol 4- phosphate (PtdIns4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). PtdIns(4,5)P2 is involved in a variety of cellular processes and is the substrate to form phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3), another second messenger. The majority of PtdIns(4,5)P2 is thought to occur via type I phosphatidylinositol 4-phosphate 5-kinases given the abundance of PtdIns4P. Participates in a variety of cellular processes such as actin cytoskeleton organization, cell adhesion, migration and phagocytosis. Required for membrane ruffling formation, actin organization and focal adhesion formation during directional cell migration by controlling integrin-induced translocation of RAC1 to the plasma membrane. Together with PIP5K1C is required for phagocytosis, but they regulate different types of actin remodeling at sequential steps. Promotes particle ingestion by activating WAS that induces Arp2/3 dependent actin polymerization at the nascent phagocytic cup. Together with PIP5K1B is required after stimulation of G-protein coupled receptors for stable platelet adhesion. Plays a role during calcium-induced keratinocyte differentiation.
Alias Symbols: Name=PIP5K1A,
Protein Interaction Partner: UBC, ITGB1BP2, HECW2, UBD, SIRT1, CSNK1A1, APP, PIP5KL1, CADPS, PLD2, PLD1, CASP3, TEC, ARF6, BTK, ARF5, ARF1,
Protein Size: 562 - 基因ID
- 8394
- UniProt
- Q99755
- 途径
- PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Inositol Metabolic Process, DNA Replication, Cell-Cell Junction Organization, Synthesis of DNA
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