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FE65 抗体 (N-Term)

APBB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5515785
发货至: 中国
  • 抗原 See all FE65 (APBB1) 抗体
    FE65 (APBB1) (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1))
    抗原表位
    • 15
    • 15
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 56
    • 38
    • 28
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 59
    • 1
    • 1
    克隆类型
    • 61
    多克隆
    标记
    • 19
    • 3
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    • 3
    • 3
    • 3
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    • 3
    • 3
    • 3
    • 3
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    This FE65 antibody is un-conjugated
    应用范围
    • 60
    • 39
    • 39
    • 14
    • 10
    • 9
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    QALTDGPREH SKSASLLFGM RNSAASDEDS SWATLSQGSP SYGSPEDTDS
    产品特性
    This is a rabbit polyclonal antibody against APBB1. It was validated on Western Blot.
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human APBB1
    Top Product
    Discover our top product APBB1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    FE65 (APBB1) (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1))
    别名
    APBB1 (APBB1 产品)
    别名
    FE65 antibody, MGC:9072 antibody, RIR antibody, apbb1 antibody, MGC80654 antibody, Fe65 antibody, Rir antibody, amyloid beta precursor protein binding family B member 1 antibody, amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) L homeolog antibody, amyloid beta (A4) precursor protein-binding, family B, member 1 antibody, APBB1 antibody, apbb1.L antibody, Apbb1 antibody
    背景
    The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    Alias Symbols: APBB1, FE65, RIR,

    Protein Size: 710
    基因ID
    322
    UniProt
    O00213
    途径
    Positive Regulation of Response to DNA Damage Stimulus
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