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RAD51 抗体 (N-Term)

This anti-RAD51 antibody is a 兔 多克隆 antibody detecting RAD51 in WB. Suitable for 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马 和 犬.
产品编号 ABIN5515419
发货至: 中国

Quick Overview for RAD51 抗体 (N-Term) (ABIN5515419)

抗原

See all RAD51 抗体
RAD51 (DNA Repair Protein Homolog 1 (RAD51))

适用

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人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, 犬

宿主

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克隆类型

  • 97
  • 72
多克隆

标记

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This RAD51 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    QLEANADTSV EEESFGPQPI SRLEQCGINA NDVKKLEEAG FHTVEAVAYA

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 94%, Human: 100%, Mouse: 100%, Rabbit: 94%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against RAD51. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N-terminal region of Human RAD51
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    RAD51 (DNA Repair Protein Homolog 1 (RAD51))

    别名

    RAD51

    背景

    The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: Name=RAD51,

    Protein Interaction Partner: BRCA1, ATRX, FBXO18, PALB2, HNRNPC, SWSAP1, HNRNPA2B1, RPA3, RPA1, RAD52, PFN1, RAD54B, AICDA, BLM, DMC1, NXF1, RECQL5, UGDH, CHEK1, BRCA2, SFR1, SWI5, NEDD8, PML, TERF2IP, TP53, MSH2, MSH6, UBC, UHRF2, RAD51AP1, WRN, POLN, MORF4L1, MDC1, RAD51C, MCPH1, S

    Protein Size: 339

    基因ID

    5888

    UniProt

    Q06609

    途径

    DNA Damage Repair
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