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MKRN1 抗体 (C-Term)

MKRN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5514960
发货至: 中国
  • 抗原 See all MKRN1 抗体
    MKRN1 (Makorin Ring Finger Protein 1 (MKRN1))
    抗原表位
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 29
    • 10
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    宿主
    • 24
    • 3
    • 2
    克隆类型
    • 26
    • 3
    多克隆
    标记
    • 20
    • 3
    • 2
    • 2
    • 1
    • 1
    This MKRN1 antibody is un-conjugated
    应用范围
    • 22
    • 17
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    SRYRAQRRNH FWELIEEREN SNPFDNDEEE VVTFELGEML LMLLAAGGDD
    产品特性
    This is a rabbit polyclonal antibody against MKRN1. It was validated on Western Blot.
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human MKRN1
    Top Product
    Discover our top product MKRN1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MKRN1 (Makorin Ring Finger Protein 1 (MKRN1))
    别名
    MKRN1 (MKRN1 产品)
    别名
    MKRN1 antibody, MGC84269 antibody, mkrn1 antibody, Makorin-1 antibody, RNF61 antibody, RFP antibody, makorin ring finger protein 1 antibody, E3 ubiquitin-protein ligase makorin-1 antibody, makorin ring finger protein 1 S homeolog antibody, makorin, ring finger protein, 1 antibody, MKRN1 antibody, LOC100393879 antibody, mkrn1.S antibody, Mkrn1 antibody
    背景
    This gene encodes a protein that belongs to a novel class of zinc finger proteins. The encoded protein functions as a transcriptional co-regulator, and as an E3 ubiquitin ligase that promotes the ubiquitination and proteasomal degradation of target proteins. The protein encoded by this gene is thought to regulate RNA polymerase II-catalyzed transcription. Substrates for this protein's E3 ubiquitin ligase activity include the capsid protein of the West Nile virus and the catalytic subunit of the telomerase ribonucleoprotein. This protein controls cell cycle arrest and apoptosis by regulating p21, a cell cycle regulator, and the tumor suppressor protein p53. Pseudogenes of this gene are present on chromosomes 1, 3, 9, 12 and 20, and on the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Alias Symbols: RNF61

    Protein Size: 482
    基因ID
    23608
    NCBI登录号
    NP_038474
    UniProt
    Q9UHC7
    途径
    Chromatin Binding
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