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Calpain 6 抗体 (Middle Region)

CAPN6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5514668
发货至: 中国
  • 抗原 See all Calpain 6 (CAPN6) 抗体
    Calpain 6 (CAPN6)
    抗原表位
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    Middle Region
    适用
    • 32
    • 6
    • 3
    宿主
    • 30
    • 3
    克隆类型
    • 30
    • 3
    多克隆
    标记
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Calpain 6 antibody is un-conjugated
    应用范围
    • 23
    • 20
    • 17
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    TIPNHKEQEW DPQKTEKYAG IFHFRFWHFG EWTEVVIDDL LPTINGDLVF
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human CAPN6
    Top Product
    Discover our top product CAPN6 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Calpain 6 (CAPN6)
    别名
    CAPN6 (CAPN6 产品)
    别名
    CAPN6 antibody, CANPX antibody, CAPNX antibody, CalpM antibody, DJ914P14.1 antibody, calpain 6 antibody, CAPN6 antibody, Capn6 antibody
    背景
    Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.

    Alias Symbols: CANPX, CAPNX, CalpM, DJ914P14.1

    Protein Size: 641
    基因ID
    827
    NCBI登录号
    NM_014289, NP_055104
    UniProt
    Q9Y6Q1
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