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Cathepsin F 抗体 (C-Term)

CTSF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5514659
发货至: 中国
  • 抗原 See all Cathepsin F (CTSF) 抗体
    Cathepsin F (CTSF)
    抗原表位
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 32
    • 12
    • 2
    • 1
    宿主
    • 30
    • 2
    • 1
    • 1
    克隆类型
    • 32
    • 2
    多克隆
    标记
    • 15
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cathepsin F antibody is un-conjugated
    应用范围
    • 16
    • 12
    • 10
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    RPLCSPWLID HAVLLVGYGN RSDVPFWAIK NSWGTDWGEK GYYYLHRGSG
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human CTSF
    Top Product
    Discover our top product CTSF Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Cathepsin F (CTSF)
    别名
    CTSF (CTSF 产品)
    别名
    CTSF antibody, MGC140519 antibody, cb420 antibody, sb:cb420 antibody, zgc:153093 antibody, LOC100101596 antibody, Ctsf antibody, ACYPI000376 antibody, catf antibody, CATSF antibody, CLN13 antibody, AI481912 antibody, cathepsin F antibody, cathepsin W antibody, CTSF antibody, ctsf antibody, Ctsf antibody, ctsw antibody, Tsp_02382 antibody
    背景
    Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.

    Alias Symbols: CATSF, CLN13

    Protein Size: 484
    基因ID
    8722
    NCBI登录号
    NM_003793, NP_003784
    UniProt
    Q9UBX1
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