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Cathepsin F 抗体

CTSF 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7255323
发货至: 中国
  • 抗原 See all Cathepsin F (CTSF) 抗体
    Cathepsin F (CTSF)
    适用
    • 31
    • 11
    • 2
    • 1
    人, 小鼠
    宿主
    • 29
    • 2
    • 1
    • 1
    克隆类型
    • 31
    • 2
    多克隆
    标记
    • 14
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cathepsin F antibody is un-conjugated
    应用范围
    • 16
    • 11
    • 10
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human CTSF (NP_003784.2).
    亚型
    IgG
    Top Product
    Discover our top product CTSF Primary Antibody
  • 应用备注
    IHC 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Cathepsin F (CTSF)
    别名
    CTSF (CTSF 产品)
    背景
    Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.
    基因ID
    8722
    UniProt
    Q9UBX1
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