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RAGE 抗体 (Middle Region)

AGER 适用: 人, 小鼠, 大鼠, 兔 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN548553
发货至: 中国
  • 抗原 See all RAGE (AGER) 抗体
    RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
    抗原表位
    • 20
    • 16
    • 16
    • 11
    • 11
    • 9
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 141
    • 81
    • 63
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, 兔
    宿主
    • 136
    • 10
    • 4
    • 2
    • 1
    克隆类型
    • 130
    • 22
    • 1
    多克隆
    标记
    • 69
    • 11
    • 10
    • 9
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RAGE antibody is un-conjugated
    应用范围
    • 125
    • 65
    • 49
    • 33
    • 27
    • 26
    • 23
    • 11
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit polyclonal antibody raised against synthetic peptide of AGER.
    特异性
    The synthetic peptide of this antibody different from the mouse and rat sequence by two amino acids.
    交叉反应
    人, 小鼠, 兔, 大鼠
    免疫原
    A synthetic peptide corresponding to amino acids at middle region of human AGER.
    亚型
    IgG
    Top Product
    Discover our top product AGER Primary Antibody
  • 应用备注
    Western Blot (1 μg/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 μg/mL)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
    储存液
    Sodium azide, Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C on dry atmosphere.
    After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Bierhaus, Haslbeck, Humpert, Liliensiek, Dehmer, Morcos, Sayed, Andrassy, Schiekofer, Schneider, Schulz, Heuss, Neundörfer, Dierl, Huber, Tritschler, Schmidt, Schwaninger, Haering, Schleicher, Kasper et al.: "Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily. ..." in: The Journal of clinical investigation, Vol. 114, Issue 12, pp. 1741-51, (2004) (PubMed).

    Chavakis, Bierhaus, Al-Fakhri, Schneider, Witte, Linn, Nagashima, Morser, Arnold, Preissner, Nawroth: "The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment." in: The Journal of experimental medicine, Vol. 198, Issue 10, pp. 1507-15, (2003) (PubMed).

    Taguchi, Blood, del Toro, Canet, Lee, Qu, Tanji, Lu, Lalla, Fu, Hofmann, Kislinger, Ingram, Lu, Tanaka, Hori, Ogawa, Stern, Schmidt: "Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases." in: Nature, Vol. 405, Issue 6784, pp. 354-60, (2000) (PubMed).

  • 抗原
    RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
    别名
    RAGE / AGER (AGER 产品)
    别名
    RAGE antibody, AGER antibody, advanced glycosylation end-product specific receptor antibody, advanced glycosylation end product-specific receptor antibody, MAPK/MAK/MRK overlapping kinase antibody, AGER antibody, Ager antibody, LOC719012 antibody
    基因ID
    177
    途径
    Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins
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