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SMAD4 抗体 (Thr277)

Name: SMAD4 抗体 (Thr277)
SKU: ABIN542927
Availability: OutOfStock

SMAD4 适用: 人 IHC (p), DB 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin-embedded human breast cancer tissue reacted with SMAD4 (phospho T277) polyclonal antibody which was peroxidase-conjugated to the secondary antibody followed by DAB staining. (SMAD4 抗体 (Thr277))

IHC

Dot blot analysis of SMAD4 (phospho T277) polyclonal antibody on nitrocellulose membrane. (SMAD4 抗体 (Thr277))

2 images

(7 references)

产品编号 ABIN542927

发货至: 中国

Datasheet as PDF

抗原 See all SMAD4 抗体

SMAD4 (SMAD Family Member 4 (SMAD4))
抗原表位
12

10

9

8

7

7

6

5

4

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1
Thr277
适用
100

42

37

4

3

3

2

2

2

2

2

2

1

1
人
宿主
89

11

1
兔
Compatible Secondaries
克隆类型
75

26
多克隆
标记
57

9

8

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1
This SMAD4 antibody is un-conjugated
应用范围
67

46

36

30

22

12

8

8

7

3

2

2

2

1

1

1

1

1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)

原理

Rabbit polyclonal antibody raised against synthetic peptide of SMAD4.

交叉反应

人

免疫原

A synthetic peptide (conjugated with KLH) corresponding to residues surrounding T277 of human SMAD4.

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anti-SMAD Family Member 4 (SMAD4) (AA 1-552) antibody
SMAD4 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3E2 unconjugated

anti-SMAD Family Member 4 (SMAD4) antibody
KO Validated SMAD4 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated

anti-SMAD Family Member 4 (SMAD4) antibody
SMAD4 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 4G1C6 unconjugated

anti-SMAD Family Member 4 (SMAD4) (AA 400-428) antibody
SMAD4 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-SMAD Family Member 4 (SMAD4) (AA 40-120) antibody
SMAD4 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-SMAD Family Member 4 (SMAD4) (AA 27-195) antibody
SMAD4 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-SMAD Family Member 4 (SMAD4) (AA 118-240) antibody
SMAD4 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-SMAD Family Member 4 (SMAD4) (AA 255-284) antibody
SMAD4 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB14714 unconjugated

anti-SMAD Family Member 4 (SMAD4) (pThr277) antibody
SMAD4 适用: 人 ELISA, IHC, IF, DB 宿主: 兔 Polyclonal unconjugated

应用备注

Dot Blot (1:500)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.

限制

仅限研究用
状态

Liquid

缓冲液

In PBS (0.09 % sodium azide)

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Zhang, Lui: "Transforming growth factor-?3 regulates cell junction restructuring via MAPK-mediated mRNA destabilization and Smad-dependent protein degradation of junctional adhesion molecule B (JAM-B)." in: Biochimica et biophysica acta, Vol. 1849, Issue 6, pp. 601-11, (2015) (PubMed).

Xiao, Ho, Liong, Nanji, Leung, Lau, Fung, Tipoe: "Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways." in: European journal of nutrition, Vol. 53, Issue 1, pp. 187-99, (2014) (PubMed).

Xiao, Xing, Huo, Fung, Liong, Ching, Xu, Chang, So, Tipoe: "Lycium barbarum polysaccharides therapeutically improve hepatic functions in non-alcoholic steatohepatitis rats and cellular steatosis model." in: Scientific reports, Vol. 4, pp. 5587, (2014) (PubMed).

Wang, Lui: "Transforming growth factor-?1 attenuates junctional adhesion molecule-A and contributes to breast cancer cell invasion." in: European journal of cancer (Oxford, England : 1990), Vol. 48, Issue 18, pp. 3475-87, (2012) (PubMed).

Horvath, Henshall, Kench, Turner, Golovsky, Brenner, ONeill, Kooner, Stricker, Grygiel, Sutherland: "Loss of BMP2, Smad8, and Smad4 expression in prostate cancer progression." in: The Prostate, Vol. 59, Issue 3, pp. 234-42, (2004) (PubMed).

Sekiya, Oda, Matsuura, Akiyama: "Transcriptional regulation of the TGF-beta pseudoreceptor BAMBI by TGF-beta signaling." in: Biochemical and biophysical research communications, Vol. 320, Issue 3, pp. 680-4, (2004) (PubMed).

Li, Xin, Xu, Huang, Zhang, Chen, Zhang, Fu, Chang: "CHIP mediates degradation of Smad proteins and potentially regulates Smad-induced transcription." in: Molecular and cellular biology, Vol. 24, Issue 2, pp. 856-64, (2003) (PubMed).
抗原

SMAD4 (SMAD Family Member 4 (SMAD4))

别名

SMAD4 (SMAD4 产品)

别名

smad4 antibody, DPC4 antibody, JIP antibody, MADH4 antibody, MYHRS antibody, AW743858 antibody, D18Wsu70e antibody, Madh4 antibody, XSmad4alpha antibody, Xsmad4 antibody, dpc4 antibody, jip antibody, madh4 antibody, xsmad4a antibody, SMAD family member 4 antibody, Smad4 protein antibody, SMAD family member 4, gene 1 L homeolog antibody, SMAD4 antibody, smad4 antibody, Smad4 antibody, smad4.1.L antibody

基因ID

4089

途径

Cell Division Cycle, Chromatin Binding, Autophagy