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BIM 抗体

BCL2L11 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN542826
发货至: 中国
  • 抗原 See all BIM (BCL2L11) 抗体
    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
    适用
    • 159
    • 101
    • 91
    • 5
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    宿主
    • 147
    • 9
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    克隆类型
    • 132
    • 30
    多克隆
    标记
    • 69
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    This BIM antibody is un-conjugated
    应用范围
    • 104
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit polyclonal antibody raised against synthetic peptide of BCL2L11.
    交叉反应
    免疫原
    A synthetic peptide (conjugated with KLH) corresponding to BH3 domain of human BCL2L11.
    Top Product
    Discover our top product BCL2L11 Primary Antibody
  • 应用备注
    Western Blot (1:1000)
    Immunohistochemistry (1:50-100)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In PBS (0.09 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Chen, Zhou: "Caspase cleavage of BimEL triggers a positive feedback amplification of apoptotic signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 5, pp. 1235-40, (2004) (PubMed).

    Sunters, Fernández de Mattos, Stahl, Brosens, Zoumpoulidou, Saunders, Coffer, Medema, Coombes, Lam: "FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines." in: The Journal of biological chemistry, Vol. 278, Issue 50, pp. 49795-805, (2003) (PubMed).

    Luciano, Jacquel, Colosetti, Herrant, Cagnol, Pages, Auberger: "Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function." in: Oncogene, Vol. 22, Issue 43, pp. 6785-93, (2003) (PubMed).

  • 抗原
    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
    别名
    Bcl-2-like 11 (BCL2L11 产品)
    别名
    bim antibody, BAM antibody, BIM antibody, BOD antibody, 1500006F24Rik antibody, Bim antibody, Bod antibody, BimL antibody, BIMEL antibody, BCL2-like 11 antibody, BCL2 like 11 antibody, BCL2-like 11 (apoptosis facilitator) antibody, bcl2l11 antibody, BCL2L11 antibody, Bcl2l11 antibody
    基因ID
    10018
    途径
    PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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