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HLA-E 抗体

HLA-E 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-E-06 unconjugated
产品编号 ABIN535268
发货至: 中国
  • 抗原 See all HLA-E 抗体
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    适用
    • 67
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 44
    • 24
    小鼠
    克隆类型
    • 46
    • 22
    单克隆
    标记
    • 31
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HLA-E antibody is un-conjugated
    应用范围
    • 42
    • 27
    • 19
    • 13
    • 13
    • 12
    • 9
    • 7
    • 3
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP)
    原理
    Mouse monoclonal antibody raised against recombinant HLA-E.
    特异性
    This antibody recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on many types of the human cells. The published results showed that This antibody cross-reacts with some classical MHC ClassI molecules (HLA-A3, -A11, -B7). However, the recent Workshop I Session on the 3rd International Conference on HLA-G (Paris, July 2003) confirmed that This antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32,-B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7.
    交叉反应
    人, 灵长类
    免疫原
    Recombinant protein corresponding to human HLA-E.
    克隆位点
    MEM-E-06
    亚型
    IgG1
    Top Product
    Discover our top product HLA-E Primary Antibody
  • 应用备注
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    In TBS, pH 8.0 (0.09 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 4°C. Do not freeze.
  • Gonen-Gross, Achdout, Arnon, Gazit, Stern, Horejsí, Goldman-Wohl, Yagel, Mandelboim: "The CD85J/leukocyte inhibitory receptor-1 distinguishes between conformed and beta 2-microglobulin-free HLA-G molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 8, pp. 4866-74, (2005) (PubMed).

    Palmisano, Contardi, Morabito, Gargaglione, Ferrara, Pistillo: "HLA-E surface expression is independent of the availability of HLA class I signal sequence-derived peptides in human tumor cell lines." in: Human immunology, Vol. 66, Issue 1, pp. 1-12, (2004) (PubMed).

    Menier, Saez, Horejsi, Martinozzi, Krawice-Radanne, Bruel, Le Danff, Reboul, Hilgert, Rabreau, Larrad, Pla, Carosella, Rouas-Freiss: "Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules." in: Human immunology, Vol. 64, Issue 3, pp. 315-26, (2003) (PubMed).

  • 抗原
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    别名
    HLA class I alpha E / HLA-E (HLA-E 产品)
    别名
    EA1.2 antibody, EA2.1 antibody, HLA-6.2 antibody, MHC antibody, QA1 antibody, major histocompatibility complex, class I, E antibody, HLA-E antibody, PATR-E antibody
    基因ID
    3133
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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