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SHP1 抗体 (C-Term)

PTPN6 适用: 人 WB, ELISA, ICC, IP 宿主: 小鼠 Monoclonal M160 unconjugated
产品编号 ABIN533154
发货至: 中国
  • 抗原 See all SHP1 (PTPN6) 抗体
    SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
    抗原表位
    • 35
    • 12
    • 7
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 119
    • 73
    • 55
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 108
    • 13
    • 1
    小鼠
    克隆类型
    • 96
    • 26
    单克隆
    标记
    • 60
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This SHP1 antibody is un-conjugated
    应用范围
    • 85
    • 33
    • 27
    • 21
    • 20
    • 14
    • 14
    • 11
    • 10
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunoprecipitation (IP)
    原理
    Mouse monoclonal antibody raised against partial recombinant PTPN6.
    特异性
    This sequence is highly conserved in rat and mouse SHP1.
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    Recombinant protein corresponding to C-terminus of human PTPN6.
    克隆位点
    M160
    亚型
    IgG1
    Top Product
    Discover our top product PTPN6 Primary Antibody
  • 应用备注
    ELISA (1:2000)
    Immunocytochemistry (1:100)
    Immunoprecipitation (5-10 µL)
    Western Blot (1:500)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In PBS (50 % glycerol, 1 mg/mL BSA, 0.05 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Jones, Craik, Gibbins, Poole: "Regulation of SHP-1 tyrosine phosphatase in human platelets by serine phosphorylation at its C terminus." in: The Journal of biological chemistry, Vol. 279, Issue 39, pp. 40475-83, (2004) (PubMed).

    Zhang, Shen, Lu, Cole: "The role of C-terminal tyrosine phosphorylation in the regulation of SHP-1 explored via expressed protein ligation." in: The Journal of biological chemistry, Vol. 278, Issue 7, pp. 4668-74, (2003) (PubMed).

    Zhang, Somani, Siminovitch: "Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cell signalling." in: Seminars in immunology, Vol. 12, Issue 4, pp. 361-78, (2000) (PubMed).

  • 抗原
    SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
    别名
    PTPN6 (PTPN6 产品)
    别名
    HCPH antibody, HPTP1C antibody, PTP-1C antibody, SH-PTP1 antibody, SHP-1 antibody, SHP-1L antibody, SHP1 antibody, DRPLA antibody, Hcph antibody, Ptp1C antibody, me antibody, motheaten antibody, Ptph6 antibody, Shp-1 antibody, fj22f05 antibody, wu:fj22f05 antibody, zgc:55501 antibody, ptpn6 antibody, protein tyrosine phosphatase, non-receptor type 6 antibody, protein tyrosine phosphatase, non-receptor type 6 L homeolog antibody, PTPN6 antibody, Ptpn6 antibody, ptpn6 antibody, ptpn6.L antibody
    基因ID
    5777
    途径
    JAK/STAT Signaling, TCR Signaling, TLR signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling
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