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SQSTM1 抗体 (AA 1-440)

SQSTM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C9 unconjugated
产品编号 ABIN522359
发货至: 中国
  • 抗原 See all SQSTM1 抗体
    SQSTM1 (Sequestosome 1 (SQSTM1))
    抗原表位
    • 17
    • 14
    • 10
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    • 1
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    AA 1-440
    适用
    • 155
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    • 17
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    宿主
    • 120
    • 37
    • 1
    • 1
    小鼠
    克隆类型
    • 112
    • 47
    单克隆
    标记
    • 101
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    • 1
    • 1
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    This SQSTM1 antibody is un-conjugated
    应用范围
    • 112
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    Western Blotting (WB), ELISA
    原理
    Mouse monoclonal antibody raised against a full-length recombinant SQSTM1.
    序列
    MASLTVKAYL LGKEDAAREI RRFSFCCSPE PEAEAEAAAG PGPCERLLSR VAALFPALRP GGFQAHYRDE DGDLVAFSSD EELTMAMSYV KDDIFRIYIK EKKECRRDHR PPCAQEAPRN MVHPNVICDG CNGPVVGTRY KCSVCPDYDL CSVCEGKGLH RGHTKLAFPS PFGHLSEGFS HSRWLRKVKH GHFGWPGWEM GPPGNWSPRP PRAGEARPGP TAESASGPSE DPSVNFLKNV GESVAAALSP LGIEVDIDVE HGGKRSRLTP VSPESSSTEE KSSSQPSSCC SDPSKPGGNV EGATQSLAEQ MRKIALESEG RPEEQMESDN CSGGDDDWTH LSSKEVDPST GELQSLQMPE SEGPSSLDPS QEGPTGLKEA ALYPHLPPEA DPRLIESLSQ MLSMGFSDEG GWLTRLLQTK NYDIGAALDT IQYSKHPPPL
    交叉反应
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    SQSTM1 (AAH03139.1, 1 a.a. ~ 440 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    1C9
    亚型
    IgG3
    Top Product
    Discover our top product SQSTM1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Myeku, Clelland, Emrani, Kukushkin, Yu, Goldberg, Duff: "Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling." in: Nature medicine, Vol. 22, Issue 1, pp. 46-53, (2016) (PubMed).

    Notte, Ninane, Arnould, Michiels: "Hypoxia counteracts taxol-induced apoptosis in MDA-MB-231 breast cancer cells: role of autophagy and JNK activation." in: Cell death & disease, Vol. 4, pp. e638, (2013) (PubMed).

    Cosse, Rommelaere, Ninane, Arnould, Michiels: "BNIP3 protects HepG2 cells against etoposide-induced cell death under hypoxia by an autophagy-independent pathway." in: Biochemical pharmacology, Vol. 80, Issue 8, pp. 1160-9, (2010) (PubMed).

    Kirkin, Lamark, Sou, Bjørkøy, Nunn, Bruun, Shvets, McEwan, Clausen, Wild, Bilusic, Theurillat, Øvervatn, Ishii, Elazar, Komatsu, Dikic, Johansen: "A role for NBR1 in autophagosomal degradation of ubiquitinated substrates." in: Molecular cell, Vol. 33, Issue 4, pp. 505-16, (2009) (PubMed).

  • 抗原
    SQSTM1 (Sequestosome 1 (SQSTM1))
    别名
    SQSTM1 (SQSTM1 产品)
    背景
    Full Gene Name: sequestosome 1
    Synonyms: A170,OSIL,PDB3,ZIP3,p60,p62,p62B
    基因ID
    8878
    途径
    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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