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- 抗原 See all BST2 抗体
- BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This BST2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 纯化方法
- Protein G Chromatography
- 免疫原
- Full length recombinant protein of BST 2 was used as the immunogen for this antibody.
- 克隆位点
- ABM52D8
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product BST2 Primary Antibody
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anti-Bone Marrow Stromal Cell Antigen 2 (BST2) (AA 1-180) antibody
BST2 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 2E6 unconjugated
anti-Bone Marrow Stromal Cell Antigen 2 (BST2) (AA 1-180) antibodyBST2 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Bone Marrow Stromal Cell Antigen 2 (BST2) (AA 1-180) antibodyBST2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Bone Marrow Stromal Cell Antigen 2 (BST2) (AA 40-180) antibodyBST2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H4 unconjugated
anti-Bone Marrow Stromal Cell Antigen 2 (BST2) (AA 49-161) antibodyBST2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Bone Marrow Stromal Cell Antigen 2 (BST2) (AA 40-180) antibodyBST2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Bone Marrow Stromal Cell Antigen 2 (BST2) (AA 40-180) antibodyBST2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bone Marrow Stromal Cell Antigen 2 (BST2) (Internal Region) antibodyBST2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bone Marrow Stromal Cell Antigen 2 (BST2) (AA 1-20) antibodyBST2 适用: 人, 小鼠 WB, FACS, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bone Marrow Stromal Cell Antigen 2 (BST2) (AA 49-161) antibodyBST2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 2-4 μg/mL, FACS: 0.5-1 μg/10^6
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS containing 0.05 % BSA, PH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- 抗原
- BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
- 别名
- BST 2 (BST2 产品)
- 别名
- BST2 antibody, CD317 antibody, TETHERIN antibody, 2310015I10Rik antibody, Bst-2 antibody, C87040 antibody, DAMP-1 antibody, GREG antibody, Damp1 antibody, bone marrow stromal cell antigen 2 antibody, bone marrow stromal antigen 2 antibody, BST2 antibody, LOC618737 antibody, Bst2 antibody
- 背景
- BST2 (Bone Marrow Stromal Antigen 2), a type II transmembrane protein also known as HM1.24/CD317, has been identified to be overexpressed in a variety of cell lines from different cancer types, including multiple myeloma, breast, lung, and kidney cancers. BST2 was discovered as a marker of differentiated B cells and was later rediscovered as a potent antiviral restriction factor with the ability to tether enveloped viruses to the cell membrane of infected cells via its GPI anchor as well as to potently inhibit virus replication in cultured cells and in vivo. It also acts as an innate immune sensor of HIV-1 that elicits an inflammatory response upon exposure. BST2 mediate host immune response by activating NF-KB through interaction with TAK1 (Transforming Growth Factor Beta-Activated Kinase 1) and TNF receptor associated factors (TRAFs) 2 and 6. In addition, BST2 induces ADCC (antibody-dependent cell cytotoxicity) against the envelope protein of HIV. BST2 was expressed constitutively on the cell surface of both CD3- and CD3+ thymocytes ex vivo.
- 分子量
- 17 kDa
- 基因ID
- 684
- UniProt
- Q10589
- 途径
- Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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