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BST2 抗体 (AA 1-20)

BST2 适用: 人, 小鼠 WB, FACS, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387967
发货至: 中国
  • 抗原 See all BST2 抗体
    BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
    抗原表位
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-20
    适用
    • 60
    • 31
    • 11
    • 1
    人, 小鼠
    宿主
    • 51
    • 8
    • 1
    克隆类型
    • 46
    • 14
    多克隆
    标记
    • 32
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BST2 antibody is un-conjugated
    应用范围
    • 51
    • 22
    • 19
    • 14
    • 14
    • 12
    • 12
    • 11
    • 9
    • 5
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human BST2
    亚型
    IgG
    Top Product
    Discover our top product BST2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
    别名
    BST2/CD317 (BST2 产品)
    别名
    BST2 antibody, CD317 antibody, TETHERIN antibody, 2310015I10Rik antibody, Bst-2 antibody, C87040 antibody, DAMP-1 antibody, GREG antibody, Damp1 antibody, bone marrow stromal cell antigen 2 antibody, bone marrow stromal antigen 2 antibody, BST2 antibody, LOC618737 antibody, Bst2 antibody
    背景

    Synonyms: CD317, TETHERIN, Bone marrow stromal antigen 2, BST-2, HM1.24 antigen, BST2

    Background: IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells. Acts as a direct physical tether, holding virions to the cell membrane and linking virions to each other. The tethered virions can be internalized by endocytosis and subsequently degraded or they can remain on the cell surface. In either case, their spread as cell-free virions is restricted. Its target viruses belong to diverse families, including retroviridae: human immunodeficiency virus type 1 (HIV-1), human immunodeficiency virus type 2 (HIV-2), simian immunodeficiency viruses (SIVs), equine infectious anemia virus (EIAV), feline immunodeficiency virus (FIV), prototype foamy virus (PFV), Mason-Pfizer monkey virus (MPMV), human T-cell leukemia virus type 1 (HTLV-1), Rous sarcoma virus (RSV) and murine leukemia virus (MLV), flavivirideae: hepatitis C virus (HCV), filoviridae: ebola virus (EBOV) and marburg virus (MARV), arenaviridae: lassa virus (LASV) and machupo virus (MACV), herpesviridae: kaposis sarcoma-associated herpesvirus (KSHV), rhabdoviridae: vesicular stomatitis virus (VSV), orthomyxoviridae: influenza A virus, and paramyxoviridae: nipah virus. Can inhibit cell surface proteolytic activity of MMP14 causing decreased activation of MMP15 which results in inhibition of cell growth and migration. Can stimulate signaling by LILRA4/ILT7 and consequently provide negative feedback to the production of IFN by plasmacytoid dendritic cells in response to viral infection. Plays a role in the organization of the subapical actin cytoskeleton in polarized epithelial cells.

    基因ID
    684
    UniProt
    Q10589
    途径
    Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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