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IL-37 抗体

IL37 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5027737
发货至: 中国
  • 抗原 See all IL-37 (IL37) 抗体
    IL-37 (IL37) (Interleukin 37 (IL37))
    适用
    • 33
    • 2
    • 1
    宿主
    • 25
    • 8
    克隆类型
    • 25
    • 8
    多克隆
    标记
    • 20
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-37 antibody is un-conjugated
    应用范围
    • 22
    • 13
    • 12
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Protein A Chromatography
    免疫原
    Full length recombinant IL-37 protein was used as the immunogen for this antibody.
    亚型
    IgG
    Top Product
    Discover our top product IL37 Primary Antibody
  • 应用备注
    WB: 2-4 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    IL-37 (IL37) (Interleukin 37 (IL37))
    别名
    IL-37 (IL37 产品)
    别名
    FIL1 antibody, FIL1(ZETA) antibody, FIL1Z antibody, IL-1F7 antibody, IL-1H antibody, IL-1H4 antibody, IL-1RP1 antibody, IL-37 antibody, IL1F7 antibody, IL1H4 antibody, IL1RP1 antibody, interleukin 37 antibody, IL37 antibody
    背景
    IL-37 (Interleukin-37) is a member of IL-1 family and is primarily an anti-inflammatory cytokine, which reduces systemic and local inflammation. There are five different splice variants of IL-37 termed IL-37a-e, where Isoform IL-37b is the largest isoform. IL-37 has significant sequence similarity with IL-18 and highly expressed in inflammatory tissues, which inhibits the excessive inflammatory response. The expression is highly induced by several toll-like receptor (TLR) ligands and pro-inflammatory cytokines such as IL-1beta, TNF-alpha, IFN-gamma. IL-37 is a potent inhibitor of innate immunity by shifting the cytokine equilibrium away from excessive inflammation.
    分子量
    20 kDa
    基因ID
    27178
    UniProt
    Q9NZH6
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