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IL-37 抗体

The 兔 多克隆 anti-IL-37 antibody (ABIN1169178) specifically detects IL-37 in WB, IHC, ELISA 和 IP. The antibody is reactive with 人 samples.
产品编号 ABIN1169178
发货至: 中国
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Quick Overview for IL-37 抗体 (ABIN1169178)

抗原

See all IL-37 (IL37) 抗体
IL-37 (IL37) (Interleukin 37 (IL37))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL-37 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
  • 原理

    anti-IL-37 (human), pAb

    特异性

    Recognizes human IL-37. Detects a band of ~30 kDa by Western blot.

    产品特性

    Polyclonal Antibody. Recognizes human IL-37. Detects a band of ~30 kDa by Western blot. Source: Rabbit. Applications: ELISA, IHC, IP, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. IL-37 (IL-1F7, IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor (IL-18R) and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide (LPS)-induced immunological reaction and LPS-induced osteoclast formation and bone resorption.

    过滤

    0.2 μm filtered

    免疫原

    Recombinant human IL-37.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.2μm-filtered solution in PBS, pH 7.4.

    储存液

    Without preservative

    注意事项

    After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    +4°C

    -20°C

    Stable for at least 6 months after receipt when stored at -20°C.

    有效期

    6 months
  • 抗原

    IL-37 (IL37) (Interleukin 37 (IL37))

    别名

    IL-37

    背景

    Alternate Names/Synonyms: Interleukin-1 Family Member 7, IL-1F7, FIL1 zeta, IL-1X, Interleukin-1 Homolog 4, IL-1H4, Interleukin-1 zeta, IL-1 zeta, IL-1RP1, IL1F7, FIL1Z, IL1H4, IL1RP1

    Product Description: IL-37 (IL-1F7, IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor (IL-18R) and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide (LPS)-induced immunological reaction and LPS-induced osteoclast formation and bone resorption.

    UniProt

    Q9NZH6
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