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IL-37 抗体

IL37 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1169178
发货至: 中国
  • 抗原 See all IL-37 (IL37) 抗体
    IL-37 (IL37) (Interleukin 37 (IL37))
    适用
    • 32
    • 2
    • 1
    宿主
    • 24
    • 8
    克隆类型
    • 24
    • 8
    多克隆
    标记
    • 19
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-37 antibody is un-conjugated
    应用范围
    • 21
    • 12
    • 11
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
    特异性
    Recognizes human IL-37. Detects a band of ~30 kDa by Western blot.
    交叉反应
    过滤
    0.2 μm filtered
    免疫原
    Recombinant human IL-37.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
    储存液
    Without preservative
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    有效期
    6 months
  • 抗原
    IL-37 (IL37) (Interleukin 37 (IL37))
    别名
    IL-37 (IL37 产品)
    别名
    FIL1 antibody, FIL1(ZETA) antibody, FIL1Z antibody, IL-1F7 antibody, IL-1H antibody, IL-1H4 antibody, IL-1RP1 antibody, IL-37 antibody, IL1F7 antibody, IL1H4 antibody, IL1RP1 antibody, interleukin 37 antibody, IL37 antibody
    背景
    IL-37 (IL-1F7, IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor (IL-18R) and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide (LPS)-induced immunological reaction and LPS-induced osteoclast formation and bone resorption.
    UniProt
    Q9NZH6
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