TRIM29 抗体 (AA 2-291)
Quick Overview for TRIM29 抗体 (AA 2-291) (ABIN5027599)
抗原
See all TRIM29 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 2-291
-
纯化方法
- Protein G Chromatography
-
免疫原
- A partial length recombinant Trim29 protein (amino acids 2-291) was used as the immunogen for this antibody.
-
亚型
- IgG2b kappa
-
-
anti-Tripartite Motif Containing 29 (TRIM29) (AA 451-588) antibody
TRIM29 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8C8G5 unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (Internal Region) antibodyVerified TRIM29 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 1-200) antibodyTRIM29 适用: 人 ELISA, IHC, Coat, StM 宿主: 小鼠 Monoclonal TRIM29-1041 unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (Internal Region) antibodyTRIM29 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 1-200) antibodyTRIM29 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-629M unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 309-588) antibodyTRIM29 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (C-Term) antibodyTRIM29 适用: 人, 小鼠, 大鼠, Cow, 马, 豚鼠, 犬, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 1-588) antibodyTRIM29 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 1-200) antibodyTRIM29 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal TRIM29-1042 unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 253-283) antibodyTRIM29 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 2-4 μg/mL, IHC: 1 μg/mL
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- PBS containing 0.05 % BSA, PH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
-
- TRIM29 (Tripartite Motif Containing 29 (TRIM29))
-
别名
- Trim29
-
背景
- TRIM29 (Tripartite motif-containing 29) is a member of the tripartite motif (TRIM) family of transcription factors, characterized by the conserved RING finger, B-box, and coiled-coil domains. The TRIM family has been implicated in a variety of physiologic processes including development, apoptosis and epithelial-mesenchymal transition (EMT). Depending on a tumor types, TRIM29 also may function as an oncogene or a tumor suppressor. As an oncogene, it facilitates tumor cell proliferation and invasion through stabilization of Beta-catenin. The mechanisms may also involve deactivation of p53 activity and promoting cell survival by inhibiting proapoptotic genes regulated by p53. As a histone binding protein TRIM29 is responsible for DDR (DNA damage response). It functions as a scaffold protein to assemble DNA repair proteins into chromatin followed by efficient activation of DDR. TRIM29 binds to modified histone H3 and H4 tails in the context of nucleosomes. Furthermore, chromatin binding of TRIM29 is required for the phosphorylation of H2AX nucleosomes and cell viability in response to ionizing radiation.
-
分子量
- 65 kDa
-
基因ID
- 23650
-
UniProt
- Q14134
-
途径
- p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
抗原
-
