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PACS1 抗体 (AA 150-400)

PACS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5027422
发货至: 中国
  • 抗原 See all PACS1 抗体
    PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))
    抗原表位
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-400
    适用
    • 14
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 13
    克隆类型
    • 14
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    This PACS1 antibody is un-conjugated
    应用范围
    • 10
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Protein A Chromatography
    免疫原
    A partial length recombinant PACS-1 protein (amino acids 150-400) was used as the immunogen for this antibody.
    亚型
    IgG
    Top Product
    Discover our top product PACS1 Primary Antibody
  • 应用备注
    WB: 1-3 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))
    别名
    PACS-1 (PACS1 产品)
    别名
    MRD17 antibody, AI325977 antibody, Pacs-1 antibody, phosphofurin acidic cluster sorting protein 1 antibody, PACS1 antibody, Pacs1 antibody
    背景
    PACS1 or phosphofurin acidic cluster sorting protein 1 belongs to the PACS familyof proteins and is involved in protein trafficking. PACS1 contains an acidic cluster sorting motifs and plays an important role in the localization of trans-Golgi network (TGN) membrane proteins. It has also been implicated in secretory granule biogenesis. In order to enable HIV-1 to escape immune surveillance, PACS-1 is also reported to be involved in HIV-1 Nef-mediated removal of MHC-I from the cell surface to the trans-golgi network. Diseases caused by mutation in this gene include mental retardation (MRD17) and AIDS. PACS1 has expression in adipose tissue, liver, spleen, bone, blood, brain. It has 2 isoforms produced by alternative splicing.
    分子量
    106 kDa
    基因ID
    55690
    UniProt
    Q6VY07
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