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PACS1 抗体 (AA 430-480)

The 兔 多克隆 anti-PACS1 antibody (ABIN6992139) specifically detects PACS1 in WB, ELISA, IHC (p) 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6992139
发货至: 中国
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Quick Overview for PACS1 抗体 (AA 430-480) (ABIN6992139)

抗原

See all PACS1 抗体
PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

适用

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人, 小鼠, 大鼠

宿主

  • 13

克隆类型

  • 14
多克隆

标记

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This PACS1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

    • 4
    • 2
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    • 1
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    AA 430-480

    特异性

    PACS1 antibody is human, mouse and rat reactive. Multiple isoforms of PACS1 are known to exist. PACS1 antibody is predicted to not cross-react with PACS2.

    纯化方法

    PACS1 antibody is affinity chromatography purified via peptide column.

    免疫原

    PACS1 antibody was raised against a 17 amino acid peptide near the center of human PACS1. The immunogen is located within amino acids 430 - 480 of PACS1.

    亚型

    IgG
  • 应用备注

    PACS1 antibody can be used for detection of PACS1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PACS1 antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    PACS1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

    别名

    PACS1

    背景

    The phosphofurin acidic cluster sorting protein 1 (PACS1), belongs to the PACS family of cytosolic connector proteins that localize different membrane proteins to the trans-Golgi network (TGN) (1,2). Mutations in PACS1 cause defects in cranial-neural crest migration during early development, leading to a recognizable intellectual disability syndrome (3). PACS1, along with the related protein PACS2, also plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance (4).

    分子量

    Predicted: 106 kDa

    Observed: 105 kDa

    基因ID

    55690

    NCBI登录号

    NP_060496

    UniProt

    Q6VY07
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