PACS1 抗体 (AA 430-480)
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Quick Overview for PACS1 抗体 (AA 430-480) (ABIN6992139)
抗原
See all PACS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 430-480
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特异性
- PACS1 antibody is human, mouse and rat reactive. Multiple isoforms of PACS1 are known to exist. PACS1 antibody is predicted to not cross-react with PACS2.
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纯化方法
- PACS1 antibody is affinity chromatography purified via peptide column.
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免疫原
- PACS1 antibody was raised against a 17 amino acid peptide near the center of human PACS1. The immunogen is located within amino acids 430 - 480 of PACS1.
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亚型
- IgG
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应用备注
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PACS1 antibody can be used for detection of PACS1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PACS1 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PACS1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))
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别名
- PACS1
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背景
- The phosphofurin acidic cluster sorting protein 1 (PACS1), belongs to the PACS family of cytosolic connector proteins that localize different membrane proteins to the trans-Golgi network (TGN) (1,2). Mutations in PACS1 cause defects in cranial-neural crest migration during early development, leading to a recognizable intellectual disability syndrome (3). PACS1, along with the related protein PACS2, also plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance (4).
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分子量
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Predicted: 106 kDa
Observed: 105 kDa -
基因ID
- 55690
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NCBI登录号
- NP_060496
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UniProt
- Q6VY07
抗原
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