IKKi/IKKe 抗体 (AA 2-203)
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- 抗原 See all IKKi/IKKe (IKBKE) 抗体
- IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))
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抗原表位
- AA 2-203
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IKKi/IKKe antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Protein G Chromatography
- 免疫原
- A partial length recombinant Ikke protein (amino acids 2-203) was used as the immunogen for this antibody.
- 克隆位点
- ABM13C7
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product IKBKE Primary Antibody
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anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) antibody
IKBKE 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (AA 495-716) antibodyIKBKE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (C-Term) antibodyIKBKE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (AA 701-716) antibodyIKBKE 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) antibodyIKBKE 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (AA 541-640) antibodyIKBKE 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1F7 unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (AA 544-680) antibodyIKBKE 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) antibodyIKBKE 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (pThr501) antibodyIKBKE 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (AA 1-257) antibodyIKBKE 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6B4B5 unconjugated
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- 应用备注
- WB: 2-4 μg/mL, IHC: 10-20 μg/mL
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS containing 0.05 % BSA, PH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- 抗原
- IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))
- 别名
- Ikke/Ikki/TBK1 (IKBKE 产品)
- 别名
- zgc:100844 antibody, IKBKE antibody, MGC130907 antibody, IKK-E antibody, IKK-i antibody, IKKE antibody, IKKI antibody, AW558201 antibody, IKKepsilon antibody, Ikki antibody, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon antibody, inhibitor of nuclear factor kappa B kinase subunit epsilon antibody, inhibitor of nuclear factor kappa B kinase subunit epsilon L homeolog antibody, inhibitor of kappaB kinase epsilon antibody, IKBKE antibody, ikbke antibody, ikbke.L antibody, Ikbke antibody
- 背景
- Ikke is a member of the IKK (IKappaB kinase) family that has been identified as an oncogenic protein and found to be up-regulated in breast cancer, ovarian cancer and prostate cancer. The Ikke protein has 33 % and 31 % identity at the amino acid level with Ikka and Ikkb, respectively and is primarily activated by interferon and mediates interferon signaling. The activated Ikke stimulates the transcription factor interferon regulatory factors 3 and phosphorylates signal transducer and activator of transcription. Ikke also shares some function with Ikka and Ikkb to activate NF- KappaB pathway by phosphorylation and degradation of IKappaBalpha. However, Ikke mainly mediates NF-KappaB activation induced by interferon, phorbol 12-myristate 13-acetate or the T-cell receptor, but not by tumor necrosis factor and interleukin 1, which activate Ikka and Ikkb. Ikke is predominantly expressed and active in peripheral blood leukocytes, pancreas, thymus, and spleen and contributes to IRF as well as NF-KappaB activation.
- 分子量
- 76
- 基因ID
- 9641
- UniProt
- Q14164
- 途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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