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RBCK1 抗体 (AA 121-333)
RBCK1
适用: 人
WB
宿主: 兔
Polyclonal
unconjugated
RBCK1抗体详情
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抗原
See all RBCK1 抗体
RBCK1
(RanBP-Type and C3HC4-Type Zinc Finger Containing 1 (RBCK1))
抗原表位
All epitopes for RBCK1 抗体
AA 121-333
适用
All reactivities for RBCK1 抗体
人
宿主
All hosts for RBCK1 抗体
兔
克隆类型
All clonalities for RBCK1 抗体
多克隆
标记
All conjugates for RBCK1 抗体
This RBCK1 antibody is un-conjugated
应用范围
All applications for RBCK1 抗体
Western Blotting (WB)
纯化方法
Protein A Chromatography
免疫原
A partial length recombinant HOIL-1L/RBCK1 protein (amino acids 121-333) was used as the immunogen for this antibody.
亚型
IgG
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Alternatives
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使用细节
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应用备注
WB: 2-4 μg/mL
限制
仅限研究用
贮存及处理
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浓度
0.5 mg/mL
缓冲液
PBS containing 0.05 % BSA, PH 7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C/-20 °C
储存方法
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
RBCK1目标详情
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抗原
RBCK1
(RanBP-Type and C3HC4-Type Zinc Finger Containing 1 (RBCK1))
别名
HOIL-1L/RBCK1 (RBCK1 产品 )
别名
RBCK1 antibody, C20orf18 antibody, HOIL-1 antibody, HOIL1 antibody, RBCK2 antibody, RNF54 antibody, UBCE7IP3 antibody, XAP3 antibody, XAP4 antibody, ZRANB4 antibody, C20ORF18 antibody, AL033326 antibody, HOIL-1L antibody, UIP28 antibody, Ubce7ip3 antibody, Pkcbpb15 antibody, zgc:91964 antibody, SHANK-associated RH domain interactor antibody, RANBP2-type and C3HC4-type zinc finger containing 1 antibody, ranBP-type and C3HC4-type zinc finger-containing protein 1 antibody, RanBP-type and C3HC4-type zinc finger containing 1 antibody, SHARPIN antibody, RBCK1 antibody, LOC100411512 antibody, Rbck1 antibody, rbck1 antibody
背景
RBCK1 (RanBP-type and C3HC4-type zinc finger containing 1) is a transcription factor belonging to the RING-IBR protein family. It shuttles between the nucleus and cytoplasm, possessing both the nuclear export and localization signals within its amino acid sequence. RBCK1 deficiency causes polyglucosan storage myopathy associated with progressive muscle weakness and cardiomyopathy. RBCK1 negatively regulates the cellular antiviral response. RBCK1 regulates cell cycle progression and proliferation of ERalpha (estrogen receptor alpha)-positive breast cancer cells by supporting transcription of ERalpha and cyclin B1.
分子量
58 kDa
基因ID
10616
UniProt
Q9BYM8
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