DNMT1 抗体 (AA 128-429)
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- 抗原 See all DNMT1 抗体
- DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
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抗原表位
- AA 128-429
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DNMT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 交叉反应
- 小鼠
- 纯化方法
- Protein G Chromatography
- 免疫原
- A partial length recombinant DNMT1 protein (amino acids 128-429) was used as the immunogen for this antibody.
- 克隆位点
- ABM13B2
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product DNMT1 Primary Antibody
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anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1-270) antibody
DNMT1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) antibodyDNMT1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) antibodyKO Validated DNMT1 适用: 人 WB, IHC, IP, ChIP, IF 宿主: 兔 Monoclonal unconjugated
anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1448-1594) antibodyDNMT1 适用: 人, 猴 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 7C11A2 unconjugated
anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 21-120) antibodyDNMT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1-270) antibodyDNMT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 881-914) antibodyDNMT1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB51461 unconjugated
anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) antibodyDNMT1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 637-650) antibodyDNMT1 适用: 人 WB, IHC, IP, ChIP 宿主: 小鼠 Monoclonal 60B1220-1 unconjugated
anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1317-1616) antibodyDNMT1 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1D5G2 unconjugated
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- 应用备注
- WB: 2-4 μg/mL, IHC: 5 μg/mL, FACS: 0.5 μg/10^6 cells
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS containing 0.05 % BSA, PH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- 抗原
- DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
- 别名
- Dnmt1 (DNMT1 产品)
- 别名
- cb1075 antibody, cb983 antibody, dmnt1 antibody, fb05h01 antibody, mta antibody, wu:fb05h01 antibody, ADCADN antibody, AIM antibody, CXXC9 antibody, DNMT antibody, HSN1E antibody, MCMT antibody, DDM2 antibody, DECREASED DNA METHYLATION 2 antibody, DMT01 antibody, DMT1 antibody, DNA METHYLTRANSFERASE antibody, DNA METHYLTRANSFERASE 01 antibody, DNA METHYLTRANSFERASE 1 antibody, MET2 antibody, METHYLTRANSFERASE 2 antibody, METHYLTRANSFERASE I antibody, METI antibody, methyltransferase 1 antibody, Cxxc9 antibody, Dnmt antibody, Dnmt1o antibody, MTase antibody, Met-1 antibody, Met1 antibody, MommeD2 antibody, m.MmuI antibody, DNA methyltransferase 1 antibody, DNA (cytosine-5-)-methyltransferase 1 antibody, methyltransferase 1 antibody, DNA methyltransferase (cytosine-5) 1 antibody, DNMT1 antibody, dnmt1 antibody, Dnmt1 antibody, MET1 antibody
- 背景
- Dnmt1(DNA (cytosine-5-)-methyltransferase 1 ) is one of the most abundant DNA methyltransferase in mammalian tissues, where it associates with the replication machinery and restores symmetrical methylation at hemimethylated CpG sites generated by the semi-conservative DNA replication process. Dnmt1 comprises a regulatory N-terminal region and a C-terminal catalytic domain connected by a linker of seven glycine-lysine repeats. The N-terminal part contains a PCNA binding domain (PBD), a heterochromatin targeting sequence (TS), a CXXC-type zinc finger domain and two Bromo-Adjacent Homology domains (BAH1 and BAH2). The C-terminal domains of mammalian Dnmts contain all ten catalytic motifs identified in bacterial DNA (cytosine-5) methyltransferases. Dnmt1 maintains methylation patterns with high fidelity and is essential for embryonic development and genome integrity. The molecules interacting with Dnmt1, including RNA polymerase II, some RNA-binding proteins, and some specific Dnmt1-inhibitory RNA molecules are involved in chromatin organization, DNA repair, cell cycle regulation, and apoptosis.
- 分子量
- 183
- 基因ID
- 1786
- UniProt
- P26358
- 途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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