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Cyclin D1 抗体 (AA 108-322)

CCND1 适用: 人 IHC 宿主: 小鼠 Monoclonal ABM47F5 unconjugated
产品编号 ABIN5027125
发货至: 中国
  • 抗原 See all Cyclin D1 (CCND1) 抗体
    Cyclin D1 (CCND1)
    抗原表位
    • 22
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    AA 108-322
    适用
    • 230
    • 126
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    • 38
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    • 10
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    • 4
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    宿主
    • 201
    • 53
    • 1
    小鼠
    克隆类型
    • 192
    • 61
    单克隆
    标记
    • 112
    • 28
    • 20
    • 9
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    • 5
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    This Cyclin D1 antibody is un-conjugated
    应用范围
    • 193
    • 88
    • 65
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    • 41
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    • 27
    • 22
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    • 12
    • 6
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    Immunohistochemistry (IHC)
    纯化方法
    Protein G Chromatography
    免疫原
    A partial length recombinant Cyclin D1 protein (amino acids 108-322) was used as the immunogen for this antibody.
    克隆位点
    ABM47F5
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CCND1 Primary Antibody
  • 应用备注
    IHC: 5-10 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    Cyclin D1 (CCND1)
    别名
    Cyclin D1 (CCND1 产品)
    别名
    BCL1 antibody, D11S287E antibody, PRAD1 antibody, U21B31 antibody, AI327039 antibody, CycD1 antibody, Cyl-1 antibody, bcl-1 antibody, cD1 antibody, cb161 antibody, cycd1 antibody, etID37810.7 antibody, fb52e01 antibody, fc45c08 antibody, fc83a12 antibody, id:ibd1198 antibody, wu:fb52e01 antibody, wu:fc45c08 antibody, wu:fc83a12 antibody, ccnd1b antibody, prad1 antibody, ccnd1 antibody, ccnd1a antibody, bcl1 antibody, d11s287e antibody, u21b31 antibody, CCND1 antibody, cyclin D1 antibody, cyclin D1 S homeolog antibody, cyclin D1 L homeolog antibody, CCND1 antibody, Ccnd1 antibody, ccnd1 antibody, ccnd1.S antibody, ccnd1.L antibody
    背景
    Cyclin D1 (CCND1) is an important positive regulator of the G1/S phase of the cell cycle. It regulate cell cycle transition from G1 phase to S phase It is a well-established human oncogene which is frequently amplified or overexpressed in cancers (25409185). Cyclin D1b is one of two proteins translated from Cyclin D1 transcripts (isoforms a and b) that are generated due to gene polymorphism. Low Cyclin D1b expression in cervical cancer tissue, with an expression level in moderately or poorly differentiated tissues was significantly lower than that in well-differentiated tissues (25120779). Diseases associated with CCND1 include multiple myeloma and mantle cell lymphoma.
    基因ID
    23582
    UniProt
    O95273
    途径
    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling
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