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CD11c 抗体 (AA 620-835)

ITGAX 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal ABM4C58 unconjugated
产品编号 ABIN5027081
发货至: 中国
  • 抗原 See all CD11c (ITGAX) 抗体
    CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
    抗原表位
    • 17
    • 9
    • 8
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 620-835
    适用
    • 153
    • 55
    • 13
    • 12
    • 10
    • 9
    • 9
    • 5
    宿主
    • 106
    • 50
    • 18
    • 14
    • 5
    小鼠
    克隆类型
    • 145
    • 43
    • 2
    单克隆
    标记
    • 70
    • 15
    • 15
    • 13
    • 11
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD11c antibody is un-conjugated
    应用范围
    • 117
    • 48
    • 47
    • 45
    • 35
    • 24
    • 14
    • 8
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC)
    纯化方法
    Protein G Chromatography
    免疫原
    A partial length recombinant CD11c protein (amino acids 620-835) was used as the immunogen for this antibody.
    克隆位点
    ABM4C58
    亚型
    IgG2b kappa
    Top Product
    Discover our top product ITGAX Primary Antibody
  • 应用备注
    IHC: 5-10 μg/mL FACS: 0.5 - 1 μg//10^6 cells
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
    别名
    CD11c (ITGAX 产品)
    别名
    CD11C antibody, SLEB6 antibody, RGD1561123 antibody, AI449405 antibody, Cd11c antibody, Cr4 antibody, N418 antibody, integrin subunit alpha X antibody, integrin alpha X antibody, ITGAX antibody, Itgax antibody
    背景
    CD11c/CD18 ( p150/95, or complement receptor 4, CR4) is a monocyte/macrophage-enriched integrin that has been reported to bind to a variety of ligands. These include cell surface proteins (LPS, ICAM-1, ICAM-2, ICAM-4 and VCAM-1), extracellular matrix proteins (collagen I), and soluble ligands (iC3b, heparin and fibrinogen). It is expressed in macrophages, monocytes, granulocytes, subsets of T and B cells, and dendritic cells. CD11c functions as a cell surface receptor for numerous soluble factors and proteins. The interaction mediates leukocyte interactions with other cell types and is a signal transducing receptor. It is found primarily on myeloid cells, where its expression is regulated both during differentiation and during monocyte maturation into tissue macrophages.
    基因ID
    3687
    UniProt
    P20702
    途径
    Complement System, Activated T Cell Proliferation, Integrin Complex
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