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ATG16L1 抗体 (AA 35-260)

ATG16L1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5027030
发货至: 中国
  • 抗原 See all ATG16L1 抗体
    ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))
    抗原表位
    • 16
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 35-260
    适用
    • 81
    • 52
    • 34
    • 11
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    宿主
    • 84
    • 11
    • 1
    克隆类型
    • 78
    • 18
    多克隆
    标记
    • 52
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATG16L1 antibody is un-conjugated
    应用范围
    • 70
    • 30
    • 27
    • 15
    • 14
    • 13
    • 10
    • 10
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Protein A Chromatography
    免疫原
    A partial length recombinant APG16L protein (amino acids 35-260) was used as the immunogen for this antibody.
    亚型
    IgG
    Top Product
    Discover our top product ATG16L1 Primary Antibody
  • 应用备注
    WB: 2-4 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))
    别名
    APG16L (ATG16L1 产品)
    别名
    APG16L antibody, ATG16A antibody, ATG16L antibody, IBD10 antibody, WDR30 antibody, 1500009K01Rik antibody, Apg16l antibody, Atg16l antibody, Wdr30 antibody, atg16 antibody, atg16l antibody, fb57e05 antibody, wu:fb57e05 antibody, zgc:110147 antibody, autophagy related 16 like 1 antibody, autophagy related 16-like 1 (S. cerevisiae) antibody, autophagy related 16-like 1 antibody, autophagy related 16 like 1 S homeolog antibody, ATG16 autophagy related 16-like 1 (S. cerevisiae) antibody, ATG16L1 antibody, Atg16l1 antibody, atg16l1 antibody, atg16l1.S antibody
    背景
    ATG16L1/APG16L is part of a large protein complex that functions as a molecular scaffold mediating protein-protein interactions necessary for formation of the autophagosome in response to both classical and pathogen-related autophagy stimuli. APG16L protein contains an N-terminal Atg5-binding domain, a coiled-coil domain and a C-terminal WD (tryptophan-aspartic acid)-repeat domain. APG16L forms a complex with the Atg12 Atg5 conjugate and together they are actively translocated to the phagophore and are further elongated during autophagosome formation. Genetic variation in the APG16L gene has been recently implicated in Crohn's disease pathogenesis. Polymorphism within APG16L gene results in excessive production of IL-1beta and IL-6 culmunating in the inflammatory process in Crohn's disease.
    分子量
    53 kDa (Isoform)
    基因ID
    55054
    UniProt
    Q676U5
    途径
    Autophagy
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