CLEC4E 抗体
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- 抗原 See all CLEC4E 抗体
- CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CLEC4E antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Protein G Chromatography
- 免疫原
- A full length human CLEC4E protein was used as the immunogen for this antibody.
- 克隆位点
- ABM42C6
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CLEC4E Primary Antibody
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anti-C-Type Lectin Domain Family 4, Member E (CLEC4E) antibody
CLEC4E 适用: 人 WB, FACS, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2A8 unconjugated
anti-C-Type Lectin Domain Family 4, Member E (CLEC4E) (AA 41-219) antibodyCLEC4E 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-C-Type Lectin Domain Family 4, Member E (CLEC4E) (AA 1-219) antibodyCLEC4E 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D12 unconjugated
anti-C-Type Lectin Domain Family 4, Member E (CLEC4E) (AA 1-219) antibodyCLEC4E 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-C-Type Lectin Domain Family 4, Member E (CLEC4E) (AA 1-219) antibodyCLEC4E 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F2 unconjugated
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- 应用备注
- WB: 2-4 μg/mL
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS containing 0.05 % BSA, PH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- 抗原
- CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))
- 别名
- CLEC4E (CLEC4E 产品)
- 别名
- CLECSF9 antibody, MINCLE antibody, C86253 antibody, Clecsf9 antibody, Mincle antibody, CLEC4E antibody, C-type lectin domain family 4 member E antibody, C-type lectin domain family 4, member e antibody, C-type lectin domain family 4, member E antibody, CLEC4E antibody, Clec4e antibody, LOC611538 antibody
- 背景
- CLEC4E (C-type lectin domain family 4, member E), also called as Mincle, is a type II transmembrane C-type lectin receptor that specifically binds to the cord factor TDM (trehalose-6,6-dimycolate), a unique glycolipid of mycobacterial cell-surface components, and activates immune cells to confer adjuvant activity. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. CLEC4E is mainly expressed in myeloid cells, such as macrophages and neutrophils and possesses a single carbohydrate-recognition domain (CRD) in the extracellular region. It is associated with FcRgamma chain, an immunoreceptor tyrosine-based activation motif (ITAM)-containing adaptor, and acts as an activating receptor that senses damaged cells. CLEC4E is also a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPbeta) and may play a role in inflammation.
- 分子量
- 25 kDa
- 基因ID
- 26253
- UniProt
- Q9ULY5
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