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CLEC4E 抗体 (AA 51-150) (Biotin)

This anti-CLEC4E antibody is a 兔 多克隆 antibody detecting CLEC4E in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人 和 大鼠.
产品编号 ABIN1399621
发货至: 中国

Quick Overview for CLEC4E 抗体 (AA 51-150) (Biotin) (ABIN1399621)

抗原

See all CLEC4E 抗体
CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

适用

  • 31
  • 16
  • 3
人, 大鼠

宿主

  • 23
  • 9

克隆类型

  • 24
  • 8
多克隆

标记

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  • 3
  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CLEC4E antibody is conjugated to Biotin

应用范围

  • 27
  • 17
  • 16
  • 13
  • 13
  • 5
  • 5
  • 3
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
    • 10
    • 3
    • 1
    • 1
    • 1
    AA 51-150

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Cow,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CLECSF9/CLEC4E

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

    别名

    CLEC 4E

    背景

    Synonyms: C type lectin domain family 4 member E, C type lectin superfamily member 9, C-type calcium dependent carbohydrate recognition domain lectin superfamily member 9, C-type lectin domain family 4 member E, C-type lectin superfamily member 9, CLC4E_HUMAN, CLEC 4E, CLEC4E Clec4e, CLECSF9, Macrophage inducible C type lectin, Macrophage-inducible C-type lectin, MINCLE.

    Background: C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.

    基因ID

    26253
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