TIMM8A/DDP 抗体 (AA 31-97) (Alexa Fluor 680)
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- 抗原 See all TIMM8A/DDP (TIMM8A) 抗体
- TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))
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抗原表位
- AA 31-97
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TIMM8A/DDP antibody is conjugated to Alexa Fluor 680
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Cow,Sheep,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human TIMM8A
- 亚型
- IgG
- Top Product
- Discover our top product TIMM8A Primary Antibody
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anti-Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) (AA 9-97) antibody
TIMM8A 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) (AA 1-97) antibodyTIMM8A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) (AA 1-72) antibodyTIMM8A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A12 unconjugated
anti-Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) (AA 1-97) antibodyTIMM8A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) (AA 1-97) antibodyTIMM8A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) antibodyTIMM8A 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))
- 别名
- TIMM8A (TIMM8A 产品)
- 别名
- TIMM8A antibody, ddp antibody, tim8a antibody, timm8a antibody, DDP antibody, DDP1 antibody, DFN1 antibody, MTS antibody, TIM8 antibody, im:6896085 antibody, zgc:100916 antibody, Ddp1 antibody, Timm8a antibody, DXHXS1274E antibody, Fci-12 antibody, Tim8a antibody, translocase of inner mitochondrial membrane 8 homolog A (yeast) antibody, translocase of inner mitochondrial membrane 8A antibody, translocase of inner mitochondrial membrane 8 homolog A1 (yeast) antibody, translocase of inner mitochondrial membrane 8A1 antibody, TIMM8A antibody, timm8a antibody, Timm8a1 antibody
- 背景
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Synonyms: DDP 1, DDP, DDP1, Deafness dystonia protein 1, Deafness/dystonia peptide, DFN 1, DFN1, MGC12262, Mitochondrial import inner membrane translocase subunit Tim8 A, MTS, TIM 8A, TIM8A, TIMM 8A, Translocase of inner mitochondrial membrane 8 homolog A, X linked deafness dystonia protein, TIM8A_HUMAN.
Background: The majority of mitochondrial-directed proteins are encoded by the nuclear genome and are transported to the mitochondria via regulated processes involving the mitochondrial Tom and Tim proteins (1). The mitochondrial Tim protein family is comprised of a large group of evolutionarily conserved proteins that are found in most eukaryotes (1,2). Import of nuclear-encoded precursor proteins into and across the mitochondrial inner membrane is mediated by two distinct complexes, the Tim23 complex and the Tim22 complex, which differ in their substrate specificity (1). Defects in Tim proteins are implicated in several neuro-degenerative diseases, suggesting important roles for Tim proteins in development and health (3,4). Tim8A and Tim8B, which map to human chromosomes Xq22.1 and 11q23.1-q23.2, respectively, are conserved proteins of the mitochondrial intermembrane space, which are organized in hetero-oligomeric complex with Tim13 (5,6,7). Tim8A is highly expressed in fetal and adult brain (5). Tim8A is mutated in deafness dystonia syndrome, a novel type of disease that causes severe neurological defects, thought to be caused by a defective mitochondrial protein transport system (5,8).
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