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Separase 抗体 (AA 1851-1950) (Alexa Fluor 750)

ESPL1 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 750
产品编号 ABIN5010378
发货至: 中国
  • 抗原 See all Separase (ESPL1) 抗体
    Separase (ESPL1) (Extra Spindle Poles Like 1 (ESPL1))
    抗原表位
    • 17
    • 15
    • 14
    • 9
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1851-1950
    适用
    • 92
    • 11
    • 1
    宿主
    • 87
    • 5
    • 2
    克隆类型
    • 89
    • 5
    多克隆
    标记
    • 31
    • 9
    • 9
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Separase antibody is conjugated to Alexa Fluor 750
    应用范围
    • 47
    • 38
    • 25
    • 25
    • 21
    • 12
    • 12
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Separase
    亚型
    IgG
    Top Product
    Discover our top product ESPL1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Separase (ESPL1) (Extra Spindle Poles Like 1 (ESPL1))
    别名
    Separase (ESPL1 产品)
    别名
    ESP1 antibody, SEPA antibody, mp:zf637-3-001691 antibody, AL024103 antibody, AU045071 antibody, Cerp antibody, PRCE antibody, SSE antibody, extra spindle pole bodies like 1, separase antibody, extra spindle poles like 1 antibody, extra spindle pole bodies 1, separase antibody, ESPL1 antibody, espl1 antibody, Espl1 antibody
    背景

    Synonyms: Caspase like protein ESPL1, ESP 1, ESP1, ESP-1, ESPL 1, ESPL1, ESPL-1, Extra spindle poles like 1, Extra spindle poles like 1 protein, Separin, Similar to fission yeast cut1and gene, SSE, Separase, ESPL1_HUMAN.

    Background: Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21, MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]).[supplied by OMIM, Nov 2010].

    基因ID
    9700
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