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- 抗原 See all TIRAP 抗体
- TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
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抗原表位
- Center
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TIRAP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects TIRAP at Center.
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Ion exchange chromatography
- 免疫原
- TIRAP antibody was raised against a peptide corresponding to amino acids near the middle of human TIRAP.
- 亚型
- IgG
- Top Product
- Discover our top product TIRAP Primary Antibody
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anti-Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (AA 1-221) antibody
TIRAP 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (AA 1-221) antibodyTIRAP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (AA 1-221) antibodyTIRAP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (AA 1-256) antibodyTIRAP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) antibodyTIRAP 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (N-Term) antibodyTIRAP 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (pTyr86) antibodyTIRAP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western blot: 4 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
- 别名
- TIRAP (TIRAP 产品)
- 别名
- mal antibody, wyatt antibody, BACTS1 antibody, Mal antibody, MyD88-2 antibody, AA407980 antibody, C130027E04Rik antibody, Tlr4ap antibody, Wyatt antibody, toll-interleukin 1 receptor (TIR) domain containing adaptor protein antibody, TIR domain containing adaptor protein antibody, toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog antibody, toll-interleukin 1 receptor (TIR) domain-containing adaptor protein antibody, tirap antibody, TIRAP antibody, tirap.L antibody, Tirap antibody
- 背景
- Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as TIRAP and MyD88 to activate various kinases and transcription factors (4,5). In TIRAP-deficient mice, TLR signaling in response to TLR2 ligands (using either TLR1 and TLR6 as co-receptors) is totally abolished, suggesting that MyD88 and TIRAP work together and are both required for TLR2 signaling (6). Furthermore, these mice are also resistant to the toxic effects of LPS and show defects in NF-kappaB and MAP kinase activation, suggesting that TIRAP is also involed in TLR4 signaling (6,7).Synonyms: Adaptor protein Wyatt, MAL, MyD88 adapter-like protein, TIR domain-containing adapter protein, Toll/interleukin-1 receptor domain-containing adapter protein
- 基因ID
- 114609
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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