FKBP8 抗体 (AA 255-350) (Alexa Fluor 680)
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- 抗原 See all FKBP8 抗体
- FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))
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抗原表位
- AA 255-350
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FKBP8 antibody is conjugated to Alexa Fluor 680
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Dog,Cow,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human FKBP38
- 亚型
- IgG
- Top Product
- Discover our top product FKBP8 Primary Antibody
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anti-FK506 Binding Protein 8, 38kDa (FKBP8) antibody
FKBP8 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 58-190) antibodyFKBP8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) antibodyFKBP8 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 60-270) antibodyFKBP8 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 110-329) antibodyFKBP8 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 93-339) antibodyFKBP8 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 7-2# unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) antibodyFKBP8 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 110-329) antibodyFKBP8 适用: 小鼠 WB, IHC, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 1-413) antibodyFKBP8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 110-159) antibodyFKBP8 适用: 人, 小鼠, 大鼠, 犬, 马, 豚鼠, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))
- 别名
- FKBP38 (FKBP8 产品)
- 别名
- FKBP8 antibody, fkbp8 antibody, 38kDa antibody, FKBP-38 antibody, FKBP-8 antibody, Fkbp38 antibody, zgc:77672 antibody, FKBP38 antibody, FKBPr38 antibody, FK506 binding protein 8 antibody, FK506 binding protein 8 L homeolog antibody, FKBP8 antibody, fkbp8 antibody, Fkbp8 antibody, fkbp8.L antibody
- 背景
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Synonyms: 38 kDa FK 506 binding protein homolog, 38 kDa FK506-binding protein, 38 kDa FKBP, 38 kDa antibody FK506 binding protein 8, FK506 binding protein 8, 38 kDa, FK506 binding protein, 38 kDa, FK506-binding protein 8, FKBP 38, FKBP-38, FKBP-8, FKBP8, FKBP8_HUMAN, FKBPR38, hFKBP38, Peptidyl-prolyl cis-trans isomerase FKBP8, PPIase FKBP8, Rotamase, Sam11.
Background: Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis. Homomultimers or heteromultimers (Potential). Forms heterodimer with calmodulin. When activated by calmodulin and calcium, interacts with the BH4 domain of BCL2 and weakly with BCLX isoform Bcl-X(L). Does not bind and inhibit calcineurin. Interacts with HCV NS5A. Interacts with ZFYVE27, may negatively regulate ZFYVE27 phosphorylation.Tissue specificity: Widely expressed. Highest levels seen in the brain.
- 基因ID
- 23770
- 途径
- Autophagy
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