IRF7 抗体 (C-Term)
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北京 101111
Quick Overview for IRF7 抗体 (C-Term) (ABIN500058)
抗原
See all IRF7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to IRF7.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- IRF7 antibody was raised against a peptide corresponding to 14 amino acids near the carboxy-terminus of human IRF7.
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亚型
- IgG
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anti-Interferon Regulatory Factor 7 (IRF7) (pSer471), (pSer472) antibody
IRF7 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 7 (IRF7) (AA 401-503) antibodyIRF7 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 7 (IRF7) (AA 131-289) antibodyIRF7 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 7 (IRF7) (AA 1-150), (N-Term) antibodyIRF7 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 3D9 unconjugated
anti-Interferon Regulatory Factor 7 (IRF7) antibodyIRF7 适用: 人 WB, IF (cc) 宿主: 兔 Monoclonal 2A1 unconjugated
anti-Interferon Regulatory Factor 7 (IRF7) (AA 257-516) antibodyIRF7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 7 (IRF7) antibodyIRF7 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2925 unconjugated Recombinant Antibody
anti-Interferon Regulatory Factor 7 (IRF7) (AA 35-84) antibodyIRF7 适用: 人, 小鼠, 大鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 7 (IRF7) (AA 1-150) antibodyIRF7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D9 unconjugated
anti-Interferon Regulatory Factor 7 (IRF7) (N-Term) antibodyIRF7 适用: 人, 小鼠, 大鼠, Pig, 斑马鱼, 马, Cow, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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: "The transcriptional repressor Gfi1 prevents lupus autoimmunity by restraining TLR7 signaling." in: European journal of immunology, Vol. 46, Issue 12, pp. 2801-2811, (2017) (PubMed).
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: "The transcriptional repressor Gfi1 prevents lupus autoimmunity by restraining TLR7 signaling." in: European journal of immunology, Vol. 46, Issue 12, pp. 2801-2811, (2017) (PubMed).
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- IRF7 (Interferon Regulatory Factor 7 (IRF7))
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别名
- IRF7
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背景
- Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-a/b genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established.Synonyms: IRF-7, Interferon regulatory factor 7
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基因ID
- 3665
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UniProt
- Q92985
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途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy
抗原
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