我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

DcR2 抗体 (Intracellular)

Name: DcR2 抗体 (Intracellular)
SKU: ABIN499724
Availability: OutOfStock

TNFRSF10D 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of DcR2 in HeLa whole cell lysate with AP30280PU-N DcR2 antibody at 1/1000 dilution. (DcR2 抗体 (Intracellular))

Immunocytochemistry staining of HeLa cells using AP30280PU-N DcR2 antibody at 10μg/ml. (DcR2 抗体 (Intracellular))

2 images

(1 reference)

产品编号 ABIN499724

发货至: 中国

Datasheet as PDF

抗原 See all DcR2 (TNFRSF10D) 抗体

DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))
抗原表位
8

7

7

6

6

6

5

5

4

4

4

3

2

1

1

1

1

1

1

1
AA 249-263, Intracellular
适用
80

7

5

1
人, 小鼠, 大鼠
宿主
64

16
兔
Compatible Secondaries
克隆类型
63

17
多克隆
标记
35

7

7

6

5

5

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This DcR2 antibody is un-conjugated
应用范围
60

40

23

13

9

5

3

2

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

特异性

DcR2 antibody was raised against a peptide corresponding to amino acids 249 to 263 of Human DcR2 precursor.

纯化方法

Affinity Chromatography purified via peptide column

免疫原

Human DcR2 (Intracellular Domain) Peptide corresponding to amino acids 249 to 263 of Human DcR2 precursor.

亚型

IgG

Top Product

Discover our top product TNFRSF10D Primary Antibody
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) antibody
TNFRSF10D 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 56-211) antibody
TNFRSF10D 适用: 人, 小鼠 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 6E5A9 unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 56-211) antibody
TNFRSF10D 适用: 人, 猴 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 6G7G1 unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 1-210) antibody (FITC)
TNFRSF10D 适用: 人 FACS 宿主: 小鼠 Monoclonal TRAIL-R4-01 FITC

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) antibody
TNFRSF10D 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 249-263) antibody
TNFRSF10D 适用: 人, 小鼠, 大鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 249-263) antibody
TNFRSF10D 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 1-210) antibody (APC)
TNFRSF10D 适用: 人 FACS 宿主: 小鼠 Monoclonal TRAIL-R4-01 APC

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 257-386) antibody
TNFRSF10D 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 1-210) antibody (PE)
TNFRSF10D 适用: 人 FACS 宿主: 小鼠 Monoclonal TRAIL-R4-01 PE

应用备注

ELISA. Western Blot: 1/1000 to 1/2000. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
缓冲液

PBS containing 0.02 % Sodium Azide as preservative

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

Store the antibody undiluted at 2-8 °C.
Liu, Hawkins, Vilgelm, Pawlikowski, Ecsedy, Sosman, Kelley, Richmond: "Combining an Aurora Kinase Inhibitor and a Death Receptor Ligand/Agonist Antibody Triggers Apoptosis in Melanoma Cells and Prevents Tumor Growth in Preclinical Mouse Models." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 21, Issue 23, pp. 5338-48, (2015) (PubMed).
抗原

DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))

别名

CD264 / TRAILR4 (TNFRSF10D 产品)

别名

TNFRSF10D antibody, CD264 antibody, DCR2 antibody, TRAIL-R4 antibody, TRAILR4 antibody, TRUNDD antibody, TNF receptor superfamily member 10d antibody, tumor necrosis factor receptor superfamily member 10D antibody, TNFRSF10D antibody, LOC716901 antibody

背景

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor (1-3). Another member of the TRAIL receptor family was more recently identified and designated DcR2, TRAIL-R4, or TRUNDD (4-6). DcR2 has an extracellular TRAIL-binding domain but lacks intracellular death domain and does not induce apoptosis. Like DR4 and DR5, DcR2 transcript is widely expressed in normal human tissues. Overexpression of DcR2 attenuated TRAIL-induced apoptosis.Synonyms: DCR2, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TNFRSF10D, TRAIL receptor 4, TRAIL receptor with a truncated death domain, TRAIL-R4, TRUNDD, Tumor necrosis factor receptor superfamily member 10D

基因ID

8793

UniProt

Q9UBN6

途径

Apoptosis