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BAX 抗体 (N-Term)

Name: BAX 抗体 (N-Term)
SKU: ABIN499421
Availability: OutOfStock

BAX 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of Bax in HL-60 cell lysates with AP30125PU-N Bax antibody at (A) 1, (B) 2, and (C) 4 μg/ml. (BAX 抗体 (N-Term))

Immunocytochemistry staining of HL-60 cells using AP30125PU-N Bax antibody at 2 μg/ml. (BAX 抗体 (N-Term))

2 images

产品编号 ABIN499421

发货至: 中国

Datasheet as PDF

抗原 See all BAX 抗体

BAX (BCL2-Associated X Protein (BAX))
抗原表位
37

32

18

17

15

11

10

10

9

8

8

7

6

5

4

4

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
252

154

142

46

31

27

25

18

17

10

9

5

3

3

3

2

1

1

1

1

1
人
宿主
166

94

3

2
兔
Compatible Secondaries
克隆类型
180

85
多克隆
标记
137

16

13

12

10

7

6

6

6

6

6

6

5

5

5

5

5

1

1

1

1

1

1

1

1

1
This BAX antibody is un-conjugated
应用范围
237

111

72

65

52

52

51

41

39

13

12

8

5

2

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

特异性

Bax antibody was raised against a peptide corresponding to 16 amino acids near the amino-terminus of human Bax.

纯化方法

Ion exchange chromatography

免疫原

Human Bax (N-Terminus) Peptide

亚型

IgG

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anti-BCL2-Associated X Protein (BAX) (AA 1-192) antibody
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anti-BCL2-Associated X Protein (BAX) (AA 13-160) antibody
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anti-BCL2-Associated X Protein (BAX) antibody
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BAX 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB0952 unconjugated

应用备注

ELISA. Western Blot: Bax antibody can be used for detection of Bax at 2 μg/mL. . Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
缓冲液

PBS containing 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

Store the antibody undiluted at 2-8 °C.
抗原

BAX (BCL2-Associated X Protein (BAX))

别名

Bax (BAX 产品)

别名

BAX-ALPHA antibody, bax-A antibody, xBax antibody, xlbax antibody, BAX antibody, bax antibody, fj16e01 antibody, wu:fc50b10 antibody, wu:fj16e01 antibody, BCL2L4 antibody, zgc:112983 antibody, BCL2 associated X, apoptosis regulator antibody, BCL2-associated X protein L homeolog antibody, BCL2-associated X protein antibody, bcl2-associated X protein, a antibody, bcl2-associated X protein, b antibody, BAX antibody, bax.L antibody, bax antibody, baxa antibody, Bax antibody, baxb antibody

背景

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death (reviewed in 2 and 3). Bax, a pro-apoptotic Bcl-2 family member, is a cytosolic protein that changes conformation and translocates to the mitochondria following apoptotic stimuli (4,5). It is thought to share significant functional homology with Bak, another pro-apoptotic Bcl-2 family member, as disruption of bax or bak has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking both show decreased apoptotic capability (6,7).Synonyms: Apoptosis regulator BAX, BCL2-associated X protein, BCL2L4, Bcl-2-like protein 4, Bcl2-L-4

基因ID

581

NCBI登录号

NP_004315

UniProt

Q07812

途径

p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response