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- 抗原 See all BAD 抗体
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BAD antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- Bad antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human Bad.
- 纯化方法
- Ion exchange chromatography
- 免疫原
- Murine Bad / Bcl-2-like 8 Peptide
- 亚型
- IgG
- Top Product
- Discover our top product BAD Primary Antibody
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anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 101-204) antibody
BAD 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC (p), IF (p), IF (cc), FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 1-168) antibodyBAD 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 1-168) antibodyBAD 适用: 人 ELISA, WB, FACS 宿主: 小鼠 Monoclonal 1G5B3 unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 69-168) antibodyBAD 适用: 人 ELISA, WB, PLA 宿主: 小鼠 Monoclonal 3H8 unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer155) antibodyBAD 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer136) antibodyBAD 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer99) antibodyBAD 适用: 人 ELISA, DB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 92-127) antibodyBAD 适用: 人, 小鼠 ELISA, WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 1-168) antibodyBAD 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 53-81) antibodyBAD 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB06939 unconjugated
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- 应用备注
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ELISA. Western Blot: Bad antibody can be used for detection of Bad at 0.5 to 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
- Abstract
- BAD 产品
- 别名
- bad antibody, fa01b12 antibody, wu:fa01b12 antibody, wu:fa96d04 antibody, BAD antibody, BBC2 antibody, BCL2L8 antibody, AI325008 antibody, Bbc2 antibody, BCL2-associated agonist of cell death b antibody, BCL2 associated agonist of cell death antibody, BCL2-associated agonist of cell death antibody, badb antibody, BAD antibody, Bad antibody
- 背景
- Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death (reviewed in 1 and 2). Bcl-2 homology 3 (BH3) domain containing pro-apoptotic proteins, such as Bax, Bid, and Bik, form a growing subclass of the Bcl-2 family. Another such protein is the Bcl-2-antagonist of cell death (Bad). Bad regulates apoptosis by forming heterodimers with anti-apoptotic proteins Bcl-2 and Bcl-xL, thereby preventing them from binding with Bax (3). Bad activity is regulated by its phosphorylation, it is inactivated by kinases such as Akt and MAP kinase and thus promotes cell survival (4), whereas JNK-induced phosphorylation promotes the apoptotic role of Bad (5).Synonyms: BAD, BBC6, BCL2L8, Bcl-2-binding component 6, Bcl-2-like protein 8, Bcl-XL/Bcl-2-associated death promoter, Bcl2 antagonist of cell death, Bcl2-L-8
- 基因ID
- 572
- UniProt
- Q92934
- 途径
- MAPK Pathway, PI3K-Akt Signaling, RTK signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
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