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Activin A Receptor Type IB/ALK-4 抗体 (C-Term)

ACVR1B 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499207
发货至: 中国
  • 抗原 See all Activin A Receptor Type IB/ALK-4 (ACVR1B) 抗体
    Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))
    抗原表位
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    C-Term
    适用
    • 48
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    人, 小鼠
    宿主
    • 58
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    • 3
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    克隆类型
    • 61
    • 15
    多克隆
    标记
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    This Activin A Receptor Type IB/ALK-4 antibody is un-conjugated
    应用范围
    • 49
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    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to ACVR1B near the carboxy terminus.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    ACVR1B antibody was raised against a 14 amino acid peptide near the carboxy terminus of the human ACVR1B.
    亚型
    IgG
    Top Product
    Discover our top product ACVR1B Primary Antibody
  • 应用备注
    ELISA. Western Blot: ACVR1B antibody can be used for detection of ACVR1B at 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))
    别名
    Activin Receptor Type 1B (ACVR1B) (ACVR1B 产品)
    别名
    ACVR1B antibody, alk4 antibody, skr2 antibody, alk-4 antibody, xalk4 antibody, actrib antibody, acvrlk4 antibody, DKFZp469A1614 antibody, 6820432J04 antibody, ActR-IB antibody, ActRIB antibody, Acvrlk4 antibody, Alk4 antibody, SKR2 antibody, ACTRIB antibody, ACVRLK4 antibody, ALK4 antibody, Skr2 antibody, axis antibody, taram-a antibody, tarama antibody, wu:fb75f01 antibody, activin A receptor type 1B antibody, Activin receptor type-1B antibody, activin A receptor, type IB antibody, activin A receptor, type 1B antibody, activin A receptor type 1Ba antibody, ACVR1B antibody, acvr1b antibody, acv1b antibody, Acvr1b antibody, acvr1ba antibody
    背景
    Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. ACVR1B, also known as activin receptor-like kinase 4 (ALK4), is a type I receptor for activin and plays major roles in cell differentiation, growth arrest and apoptosis. Like another type I activin receptor ACVR1C, ACVR1B can mediate signaling by ligands such as Nodal, Xnr1, GDF-1/3, activin B and activin AB. In Xenopus embryos, expression of a dominant-negative form of ACVR1B blocked all mesoderm-inducing ligands, while expression of a dominant negative ACVR1C only blocked Nodal and Xnr1 signaling, suggesting that the ACVR1B and ACVR1C possess distinct functions. At least three isoforms of ACVR1B are known to exist. This antibody is predicted to have no cross-reactivity to ACVR1 or ACVR1C.Synonyms: ACTR-IB, ACVRLK4, ALK4, Activin receptor type IB, Activin receptor-like kinase 4, SKR2, Serine/threonine-protein kinase receptor R2
    基因ID
    91
    NCBI登录号
    NP_004293
    UniProt
    P36896
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