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Activin A Receptor Type IB/ALK-4 抗体 (N-Term)

ACVR1B 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal RB3740 unconjugated
产品编号 ABIN392231
发货至: 中国
  • 抗原 See all Activin A Receptor Type IB/ALK-4 (ACVR1B) 抗体
    Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))
    抗原表位
    • 15
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 39-68, N-Term
    适用
    • 47
    • 38
    • 27
    • 1
    人, 小鼠, 大鼠
    宿主
    • 57
    • 13
    • 3
    • 2
    克隆类型
    • 61
    • 14
    多克隆
    标记
    • 33
    • 12
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Activin A Receptor Type IB/ALK-4 antibody is un-conjugated
    应用范围
    • 48
    • 36
    • 13
    • 13
    • 12
    • 9
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    预测反应
    Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Activin A Receptor Type IB (ACVR1B) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the N-terminal region of human Activin A Receptor Type IB (ACVR1B).
    克隆位点
    RB3740
    亚型
    Ig Fraction
    Top Product
    Discover our top product ACVR1B Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. WB: 1:1000. FC: 1:25
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))
    别名
    Activin A Receptor Type IB (ACVR1B) (ACVR1B 产品)
    背景
    Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with a cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. The gene for ACVR1B (activin A type IB receptor) is composed of 11 exons. Alternative splicing and alternative polyadenylation result in 3 fully described transcript variants. The mRNA expression of variants 1, 2, and 3 is confirmed, and a potential fourth variant contains an alternative exon 8 and lacks exons 9 through 11, but its mRNA expression has not been confirmed.
    分子量
    56807
    基因ID
    91
    NCBI登录号
    NP_004293, NP_064732, NP_064733
    UniProt
    P36896
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