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VASP 抗体 (pSer238)

VASP 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498713
发货至: 中国
  • 抗原 See all VASP 抗体
    VASP (Vasodilator-Stimulated phosphoprotein (VASP))
    抗原表位
    • 19
    • 17
    • 15
    • 10
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    pSer238
    适用
    • 136
    • 65
    • 58
    • 11
    • 10
    • 9
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 116
    • 19
    • 2
    克隆类型
    • 111
    • 26
    多克隆
    标记
    • 79
    • 10
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This VASP antibody is un-conjugated
    应用范围
    • 104
    • 51
    • 48
    • 26
    • 22
    • 16
    • 14
    • 14
    • 12
    • 11
    • 5
    • 5
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of p-VASP protein, only when phosphorylated at Ser238.
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product VASP Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    VASP (Vasodilator-Stimulated phosphoprotein (VASP))
    别名
    VASP (VASP 产品)
    别名
    vasp antibody, MGC80889 antibody, wu:fb23b04 antibody, wu:fk84g05 antibody, zgc:110347 antibody, si:dkey-113g17.1 antibody, si:ch211-202c21.1 antibody, DDBDRAFT_0188463 antibody, DDBDRAFT_0229340 antibody, DDB_0188463 antibody, DDB_0229340 antibody, VASP antibody, vasodilator stimulated phosphoprotein S homeolog antibody, vasodilator stimulated phosphoprotein b antibody, protein enabled antibody, vasodilator-stimulated phosphoprotein antibody, vasodilator stimulated phosphoprotein a antibody, vasodilator stimulated phosphoprotein antibody, vasp.S antibody, vaspb antibody, LOC5573842 antibody, CpipJ_CPIJ004706 antibody, CpipJ_CPIJ004707 antibody, vasP antibody, vasp antibody, VASP antibody, vaspa antibody, Vasp antibody
    背景
    The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. A distantly related protein, VASP (vasodilator-stimulated phosphoprotein), is involved in the maintenance of cytoarchitecture by interacting with Actin-like filaments. VASP shares a limited degree of homology with the amino-terminus of WASP, which is frequently mutated in WAS patients. An established substrate of cAMP and cGMP dependent kinases, VASP is phosphorylated on a regulatory serine residue 157 and localizes to focal adhesions, microfilaments and highly active regions of the plasma membrane. VASP is also phosphorylated on Serine 239 by cGMP-dependent protein kinase.Synonyms: Vasodilator-stimulated phosphoprotein
    分子量
    approx. 48 kDa
    基因ID
    7408
    NCBI登录号
    NP_003361
    UniProt
    P50552
    途径
    TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
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