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VASP 产品

(Vasodilator-Stimulated phosphoprotein (VASP))

Categories

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008].

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Featured VASP Categories

VASP 抗体

High quality antibodies with extensive validation data.

VASP ELISA试剂盒

Reliable ELISA kits for a wide range of species.

VASP 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended VASP 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Dog, Human
Application WB, IHC, IHC (p)
Validations
  • (9)
Cat. No. ABIN1501698
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (5)
Cat. No. ABIN7257730
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN6150064
Quantity 100 μL
Datasheet Datasheet

Recommended VASP ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6960472
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971136
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960471
Quantity 96 tests
Datasheet Datasheet

Recommended VASP 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125705
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324923
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3096319
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our VASP Products

Wang, Long, Chen, Cui, Zhang, Zhang, Wang: "Pharmacological evidence: a new therapeutic approach to the treatment of chronic heart failure through SUR2B/Kir6.1 channel in endothelial cells." in: Acta pharmacologica Sinica, Vol. 38, Issue 1, pp. 41-55, (2016) (PubMed).

Zheng, Xiong, Wu, Chen, Chen, Fleming, Gao, Bi, Ge: "Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 6, pp. 1447-63, (2015) (PubMed).

Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: "Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy." in: Journal of proteomics, Vol. 75, Issue 7, pp. 2236-51, (2012) (PubMed).

Iyú, Glenn, White, Fox, Heptinstall: "Adenosine derived from ADP can contribute to inhibition of platelet aggregation in the presence of a P2Y12 antagonist." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 31, Issue 2, pp. 416-22, (2011) (PubMed).

Wu, Wei, Yu, Zhang, Qi, Su, Hu, Wang: "Vasodilator-stimulated phosphoprotein regulates osteosarcoma cell migration." in: Oncology reports, Vol. 26, Issue 6, pp. 1609-15, (2011) (PubMed).

Henes, Schmit, Morote-Garcia, Mirakaj, Köhler, Glover, Eldh, Walter, Karhausen, Colgan, Rosenberger: "Inflammation-associated repression of vasodilator-stimulated phosphoprotein (VASP) reduces alveolar-capillary barrier function during acute lung injury." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 12, pp. 4244-55, (2009) (PubMed).

Wang, Lu, Jin, Udo, Kandel, de Vente, Walter, Lohmann, Hawkins, Antonova: "Presynaptic and postsynaptic roles of NO, cGK, and RhoA in long-lasting potentiation and aggregation of synaptic proteins." in: Neuron, Vol. 45, Issue 3, pp. 389-403, (2005) (PubMed).

Millard, Bompard, Heung, Dafforn, Scott, Machesky, Fütterer: "Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53." in: The EMBO journal, Vol. 24, Issue 2, pp. 240-50, (2005) (PubMed).

Kühnel, Jarchau, Wolf, Schlichting, Walter, Wittinghofer, Strelkov: "The VASP tetramerization domain is a right-handed coiled coil based on a 15-residue repeat." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 49, pp. 17027-32, (2004) (PubMed).

Jensen, Selheim, Døskeland, Gear, Holmsen: "Protein kinase A mediates inhibition of the thrombin-induced platelet shape change by nitric oxide." in: Blood, Vol. 104, Issue 9, pp. 2775-82, (2004) (PubMed).

Synonyms and alternative names related to VASP

vasodilator stimulated phosphoprotein S homeolog (vasp.S), vasodilator stimulated phosphoprotein b (vaspb), protein enabled (LOC5573842), vasodilator-stimulated phosphoprotein (CpipJ_CPIJ004706), vasodilator-stimulated phosphoprotein (CpipJ_CPIJ004707), vasodilator-stimulated phosphoprotein (vasP), vasodilator-stimulated phosphoprotein (vasp), vasodilator-stimulated phosphoprotein (VASP), vasodilator stimulated phosphoprotein a (vaspa), vasodilator stimulated phosphoprotein (VASP), vasodilator-stimulated phosphoprotein (Vasp), DDBDRAFT_0188463, DDBDRAFT_0229340, DDB_0188463, DDB_0229340, MGC80889, si:ch211-202c21.1, si:dkey-113g17.1, vasp, VASP, wu:fb23b04, wu:fk84g05, zgc:110347

Protein level used designations for VASP

  • vasodilator-stimulated phosphoprotein
  • Vasodilator-stimulated phosphoprotein
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