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- 抗原 See all NEFL 抗体
- NEFL (Neurofilament, Light Polypeptide (NEFL))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NEFL antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of NF-L protein. (region surrounding Ile344)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product NEFL Primary Antibody
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anti-Neurofilament, Light Polypeptide (NEFL) antibody
NEFL 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1H3 unconjugated
anti-Neurofilament, Light Polypeptide (NEFL) (AA 400-543) antibodyNEFL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neurofilament, Light Polypeptide (NEFL) antibodyNEFL 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Neurofilament, Light Polypeptide (NEFL) antibodyNEFL 适用: 人, 大鼠, Pig, Cow, 小鸡 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal NR-4 unconjugated
anti-Neurofilament, Light Polypeptide (NEFL) (AA 1-360) antibodyNEFL 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3G2 unconjugated
anti-Neurofilament, Light Polypeptide (NEFL) antibodyNEFL 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 小鼠 Monoclonal 1H3 unconjugated
anti-Neurofilament, Light Polypeptide (NEFL) antibodyNEFL 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neurofilament, Light Polypeptide (NEFL) (AA 1-543) antibodyNEFL 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Neurofilament, Light Polypeptide (NEFL) (AA 1-284) antibodyNEFL 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Neurofilament, Light Polypeptide (NEFL) (AA 128-271) antibodyNEFL 适用: 人 IHC, IF, ELISA, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- NEFL (Neurofilament, Light Polypeptide (NEFL))
- 别名
- Neurofilament L (68kDa) (NEFL 产品)
- 别名
- NEFL antibody, nefl antibody, zgc:136626 antibody, AI847934 antibody, CMT2E antibody, NF-L antibody, NF68 antibody, Nfl antibody, CMT1F antibody, NFL antibody, XNF-L antibody, neurofilament light antibody, neurofilament, light polypeptide antibody, neurofilament, light polypeptide b antibody, neurofilament, light L homeolog antibody, NEFL antibody, neflb antibody, Nefl antibody, nefl.L antibody
- 背景
- Neurofilament-L (for neurofilament light polypeptide, or NF-L), a member of the intermediate filament family, is a major component of neuronal cytoskeletons. Neurofilaments are dynamic structures, they contain phosphorylation sites for a large number of protein kinases, including protein kinase A, protein kinase C, cyclin-dependent kinase 5, extracellular signal regulated kinase, glycogen synthase kinase-3, and stress-activated protein kinase gamma. In addition to their role in the control of axon caliber, neurofilaments may affect other cytoskeletal elements, such as microtubules and actin filaments. Changes in neurofilament phosphorylation or metabolism are frequently observed in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS),Parkinson's disease, and Alzheimer's disease.Synonyms: 68 kDa neurofilament protein, NEFL, NF-L, NF68, Neurofilament L
- 分子量
- approx. 62 kDa
- 基因ID
- 4747
- NCBI登录号
- NP_006149
- UniProt
- P07196
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