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SMAD6 抗体

SMAD6 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498566
发货至: 中国
  • 抗原 See all SMAD6 抗体
    SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
    适用
    • 51
    • 27
    • 11
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 53
    • 14
    克隆类型
    • 55
    • 12
    多克隆
    标记
    • 40
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMAD6 antibody is un-conjugated
    应用范围
    • 58
    • 39
    • 15
    • 12
    • 6
    • 3
    • 3
    • 2
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Smad6 protein. (region surrounding asn372)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product SMAD6 Primary Antibody
  • 应用备注
    Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
    别名
    SMAD6 (SMAD6 产品)
    别名
    madh6 antibody, madh7 antibody, Xsmad6 antibody, hst17432 antibody, AOVD2 antibody, HsT17432 antibody, MADH6 antibody, MADH7 antibody, Madh6 antibody, b2b390Clo antibody, Smad6-like antibody, smad6 antibody, wu:fb22g05 antibody, SMAD family member 6 antibody, SMAD family member 6a antibody, smad6 antibody, SMAD6 antibody, Smad6 antibody, smad6a antibody
    背景
    Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFbeta/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MadH6) are effectors of BMP2 and BMP4 function, while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFbeta and activinmediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFbeta signaling by interfering with TGFbeta-mediated phosphorylation of other Smad family members.Synonyms: MAD homolog 6, MADH6, Mothers against DPP homolog 6, Mothers against decapentaplegic homolog 6, SMAD 6, SMAD family member 6, SMAD-6
    分子量
    approx. 53 kDa
    基因ID
    4091
    NCBI登录号
    NP_001136333
    UniProt
    O43541
    途径
    Chromatin Binding
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