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SMAD6 抗体 (N-Term)

SMAD6 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779804
发货至: 中国
  • 抗原 See all SMAD6 抗体
    SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
    抗原表位
    • 15
    • 9
    • 9
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 51
    • 27
    • 11
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, Cow, Pig, 犬, 豚鼠, 马, 斑马鱼
    宿主
    • 53
    • 14
    克隆类型
    • 55
    • 12
    多克隆
    标记
    • 40
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMAD6 antibody is un-conjugated
    应用范围
    • 58
    • 39
    • 15
    • 11
    • 6
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    APRDASDPLA GAALEPAGGG RSREARSRLL LLEQELKTVT YSLLKR
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 91%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 86%
    产品特性
    This is a rabbit polyclonal antibody against SMAD6. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD6
    Top Product
    Discover our top product SMAD6 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 496 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
    别名
    SMAD6 (SMAD6 产品)
    别名
    madh6 antibody, madh7 antibody, Xsmad6 antibody, hst17432 antibody, AOVD2 antibody, HsT17432 antibody, MADH6 antibody, MADH7 antibody, Madh6 antibody, b2b390Clo antibody, Smad6-like antibody, smad6 antibody, wu:fb22g05 antibody, SMAD family member 6 antibody, SMAD family member 6a antibody, smad6 antibody, SMAD6 antibody, Smad6 antibody, smad6a antibody
    背景
    SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
    Alias Symbols: MADH6, MADH7, HsT17432
    Protein Interaction Partner: ITCH, SMURF2, BPIFA1, NEDD4L, WWP2, WWP1, USP15, USP11, PIGR, NASP, LYZ, KPNA2, CTBP2, CTBP1, UBC, ACVR1, UBE2O, BAMBI, STAMBP, ACTR1B, TGFBR1, MYD88, SMAD1, BMPR2, BMPR1B, BMPR1A, ACVR2B, ACVR1B, SMURF1, PELI1, CUL2, ELAVL1, SMAD5, RPS6KA5, TSC22D1, MAPK
    Protein Size: 496
    分子量
    53 kDa
    基因ID
    4091
    NCBI登录号
    NM_005585, NP_005576
    UniProt
    O43541
    途径
    Chromatin Binding
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